Development of pancreatic carcinoma in chronic calcifying pancreatitis (CCP)

Development of pancreatic carcinoma in chronic calcifying pancreatitis (CCP)

The reported incidence of pancreatic carcinoma in CCP varies from 2.9 to 25%. The pathogenetic relationship between these two conditions has been debated, but it is still not necessarily clear. Here, we report a case of pancreatic carcinoma associated with CCP. A 78-year-old man suffered from alcoho...

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Veröffentlicht in:Suizo 2005, Vol.20(2), pp.126-132
Hauptverfasser: KAKU, Toyoma, ITO, Tetsuhide, INOUE, Naoko, KAWABE, Ken, OONO, Takamasa, ARITA, Yoshiyuki
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gemcitabine
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container_end_page 132
container_issue 2
container_start_page 126
container_title Suizo
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creator KAKU, Toyoma
ITO, Tetsuhide
INOUE, Naoko
KAWABE, Ken
OONO, Takamasa
ARITA, Yoshiyuki
description The reported incidence of pancreatic carcinoma in CCP varies from 2.9 to 25%. The pathogenetic relationship between these two conditions has been debated, but it is still not necessarily clear. Here, we report a case of pancreatic carcinoma associated with CCP. A 78-year-old man suffered from alcohol-related CCP for 28 years. Follow-up computed tomography showed a pancreatic tumor in the head of the pancreas with liver and abdominal lymph node metastases. Histopathological studies of a biopsy specimen from the liver metastasis revealed adenocarcinoma. Subsequently, chemotherapy with gemcitabine was undertaken. In this case, the patient had a long history of CCP, and thus a strong association of these two diseases is suspected. We emphasize the need for close follow-up of patients with CCP to detect possible coexisting pancreatic carcinoma.
doi_str_mv 10.2958/suizo.20.126
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subjects gemcitabine
title Development of pancreatic carcinoma in chronic calcifying pancreatitis (CCP)
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