A case of acute severe hepatitis B caused by an HBV-Ae strain transmitted from her male sexual partner who also contracted acute hepatitis three months before
A 23 year old female was admitted to our hospital for general malaise and live function test abnormalities, and was diagnosed with acute hepatitis B. She showed grade-I coma and prothrombin time was prolonged. As for the source of infection, her male sexual partner was suspected because he had contr...
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Veröffentlicht in: | Kanzo 2005, Vol.46(9), pp.549-556 |
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creator | TSUCHIYA, Kaoru ASAHINA, Yasuhiro ONUKI, Yuko UEDA, Ken NISHIMURA, Yuki NAKANISHI, Hiroyuki KITAMURA, Takatoshi KUROSAKI, Masayuki UCHIHARA, Masakatsu IZUMI, Namiki |
description | A 23 year old female was admitted to our hospital for general malaise and live function test abnormalities, and was diagnosed with acute hepatitis B. She showed grade-I coma and prothrombin time was prolonged. As for the source of infection, her male sexual partner was suspected because he had contracted acute hepatitis B 3 months before. Nucleotide sequence analyses indicated that both his and her isolates segregate to genotype Ae, and showed 99.9%-identity to each other over the entire preS/S region. The partner had had sex repeatedly with prostitutes before onset of his illness. As illustrated by the present case, merely a tip of iceberg perhaps, HBV is now spreading by sex in younger generations. Some public health measures are thus warranted. |
doi_str_mv | 10.2957/kanzo.46.549 |
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She showed grade-I coma and prothrombin time was prolonged. As for the source of infection, her male sexual partner was suspected because he had contracted acute hepatitis B 3 months before. Nucleotide sequence analyses indicated that both his and her isolates segregate to genotype Ae, and showed 99.9%-identity to each other over the entire preS/S region. The partner had had sex repeatedly with prostitutes before onset of his illness. As illustrated by the present case, merely a tip of iceberg perhaps, HBV is now spreading by sex in younger generations. 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She showed grade-I coma and prothrombin time was prolonged. As for the source of infection, her male sexual partner was suspected because he had contracted acute hepatitis B 3 months before. Nucleotide sequence analyses indicated that both his and her isolates segregate to genotype Ae, and showed 99.9%-identity to each other over the entire preS/S region. The partner had had sex repeatedly with prostitutes before onset of his illness. As illustrated by the present case, merely a tip of iceberg perhaps, HBV is now spreading by sex in younger generations. 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She showed grade-I coma and prothrombin time was prolonged. As for the source of infection, her male sexual partner was suspected because he had contracted acute hepatitis B 3 months before. Nucleotide sequence analyses indicated that both his and her isolates segregate to genotype Ae, and showed 99.9%-identity to each other over the entire preS/S region. The partner had had sex repeatedly with prostitutes before onset of his illness. As illustrated by the present case, merely a tip of iceberg perhaps, HBV is now spreading by sex in younger generations. Some public health measures are thus warranted.</abstract><pub>The Japan Society of Hepatology</pub><doi>10.2957/kanzo.46.549</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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source | J-STAGE Free; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
subjects | Genotype |
title | A case of acute severe hepatitis B caused by an HBV-Ae strain transmitted from her male sexual partner who also contracted acute hepatitis three months before |
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