A case of acute severe hepatitis B caused by an HBV-Ae strain transmitted from her male sexual partner who also contracted acute hepatitis three months before

A 23 year old female was admitted to our hospital for general malaise and live function test abnormalities, and was diagnosed with acute hepatitis B. She showed grade-I coma and prothrombin time was prolonged. As for the source of infection, her male sexual partner was suspected because he had contr...

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Veröffentlicht in:Kanzo 2005, Vol.46(9), pp.549-556
Hauptverfasser: TSUCHIYA, Kaoru, ASAHINA, Yasuhiro, ONUKI, Yuko, UEDA, Ken, NISHIMURA, Yuki, NAKANISHI, Hiroyuki, KITAMURA, Takatoshi, KUROSAKI, Masayuki, UCHIHARA, Masakatsu, IZUMI, Namiki
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container_end_page 556
container_issue 9
container_start_page 549
container_title Kanzo
container_volume 46
creator TSUCHIYA, Kaoru
ASAHINA, Yasuhiro
ONUKI, Yuko
UEDA, Ken
NISHIMURA, Yuki
NAKANISHI, Hiroyuki
KITAMURA, Takatoshi
KUROSAKI, Masayuki
UCHIHARA, Masakatsu
IZUMI, Namiki
description A 23 year old female was admitted to our hospital for general malaise and live function test abnormalities, and was diagnosed with acute hepatitis B. She showed grade-I coma and prothrombin time was prolonged. As for the source of infection, her male sexual partner was suspected because he had contracted acute hepatitis B 3 months before. Nucleotide sequence analyses indicated that both his and her isolates segregate to genotype Ae, and showed 99.9%-identity to each other over the entire preS/S region. The partner had had sex repeatedly with prostitutes before onset of his illness. As illustrated by the present case, merely a tip of iceberg perhaps, HBV is now spreading by sex in younger generations. Some public health measures are thus warranted.
doi_str_mv 10.2957/kanzo.46.549
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title A case of acute severe hepatitis B caused by an HBV-Ae strain transmitted from her male sexual partner who also contracted acute hepatitis three months before
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