Clinical study of hepatitis A in Touban area (southern district of Hyougo Pref.) in 1990

From December 1989 to July 1990, we have experienced 215 cases of acute hepatitis type A in Touban area, southern district of Hyougo Prefecture. The mean age of patients was 32.7 (range 2 to 79). Fifty four patients (25%) were in their forth decade, and the number of patients over 60 was 9 (4.2%). The incidence revealed there were two epidemic peaks. The earlier was in March and the later was in May. The number of familial outbreaks was 32, in 14 families. But 20 patients (9 families) who had other patient in his residential family occurred almost same time, they were not thought to be intrafamilial infected. The biochemical data were the following. The mean total serum bilirubin was 5.2mg/dl (0.4-19.9), GOT 1417 IU/L (41-7590), GPT 1835 IU/L (40-7060). And the serum bilirubin level was correlated with patients age, that suggests the old patients tend to be serious.