Long-term follow-up Study of chronic hepatitis B virus carriers of company employees
Chronic hepatitis B virus carriers (HBV carriers) of company employees have been studied. The incidence of HBV carriers was 986 (1.17%) of 84, 456 company employees, of whom 157 (15.9%) had elevated GPT levels. The male and young HVB carriers had higher incidence of the elevated GPT level. Of 808 HB...
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| Veröffentlicht in: | Kanzo 1988/03/25, Vol.29(3), pp.294-300 |
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| container_title | Kanzo |
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| creator | SHIMA, Toshihide SETO, Yoshifumi SAKAMOTO, Yoshikuni NAKAJIMA, Toshikazu NAKASHIMA, Toshiaki OKUNO, Tadao TAKINO, Tatsuro KOTANI, Mutsumi |
| description | Chronic hepatitis B virus carriers (HBV carriers) of company employees have been studied. The incidence of HBV carriers was 986 (1.17%) of 84, 456 company employees, of whom 157 (15.9%) had elevated GPT levels. The male and young HVB carriers had higher incidence of the elevated GPT level. Of 808 HBV carriers who were followed up during about 6 years, 280 were HBeAg-positive and 528 negative at the initial examination. Of 280 HBeAg-positive carriers, 39 became seronegative (SN) and 20 were seroconverted to anti-HBe (SC). Serum GPT was elevated in all the cases before SN or SC developed and since then, returned to the normal level in most of the cases. Of carriers with persistently positive HBeAg, HBeAg titer was higher in the normal GPT carrier (4.88±1.30) than in the elevated GPT carrier (4.14±1.42). Of carriers with persistently positive anti-HBe, persistently elevated GPT values had been noted in 25 (6%). Some of them were implicated in fatty liver or post-transfusion NANB hepatitis. |
| doi_str_mv | 10.2957/kanzo.29.294 |
| format | Article |
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The incidence of HBV carriers was 986 (1.17%) of 84, 456 company employees, of whom 157 (15.9%) had elevated GPT levels. The male and young HVB carriers had higher incidence of the elevated GPT level. Of 808 HBV carriers who were followed up during about 6 years, 280 were HBeAg-positive and 528 negative at the initial examination. Of 280 HBeAg-positive carriers, 39 became seronegative (SN) and 20 were seroconverted to anti-HBe (SC). Serum GPT was elevated in all the cases before SN or SC developed and since then, returned to the normal level in most of the cases. Of carriers with persistently positive HBeAg, HBeAg titer was higher in the normal GPT carrier (4.88±1.30) than in the elevated GPT carrier (4.14±1.42). Of carriers with persistently positive anti-HBe, persistently elevated GPT values had been noted in 25 (6%). Some of them were implicated in fatty liver or post-transfusion NANB hepatitis.</description><identifier>ISSN: 0451-4203</identifier><identifier>EISSN: 1881-3593</identifier><identifier>DOI: 10.2957/kanzo.29.294</identifier><language>eng ; jpn</language><publisher>The Japan Society of Hepatology</publisher><subject>HBV carrier ; seroconversion</subject><ispartof>Kanzo, 1988/03/25, Vol.29(3), pp.294-300</ispartof><rights>The Japan Society of Hepatology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,1884,4025,27928,27929,27930</link.rule.ids></links><search><creatorcontrib>SHIMA, Toshihide</creatorcontrib><creatorcontrib>SETO, Yoshifumi</creatorcontrib><creatorcontrib>SAKAMOTO, Yoshikuni</creatorcontrib><creatorcontrib>NAKAJIMA, Toshikazu</creatorcontrib><creatorcontrib>NAKASHIMA, Toshiaki</creatorcontrib><creatorcontrib>OKUNO, Tadao</creatorcontrib><creatorcontrib>TAKINO, Tatsuro</creatorcontrib><creatorcontrib>KOTANI, Mutsumi</creatorcontrib><title>Long-term follow-up Study of chronic hepatitis B virus carriers of company employees</title><title>Kanzo</title><addtitle>Kanzo</addtitle><description>Chronic hepatitis B virus carriers (HBV carriers) of company employees have been studied. The incidence of HBV carriers was 986 (1.17%) of 84, 456 company employees, of whom 157 (15.9%) had elevated GPT levels. The male and young HVB carriers had higher incidence of the elevated GPT level. Of 808 HBV carriers who were followed up during about 6 years, 280 were HBeAg-positive and 528 negative at the initial examination. Of 280 HBeAg-positive carriers, 39 became seronegative (SN) and 20 were seroconverted to anti-HBe (SC). Serum GPT was elevated in all the cases before SN or SC developed and since then, returned to the normal level in most of the cases. Of carriers with persistently positive HBeAg, HBeAg titer was higher in the normal GPT carrier (4.88±1.30) than in the elevated GPT carrier (4.14±1.42). Of carriers with persistently positive anti-HBe, persistently elevated GPT values had been noted in 25 (6%). Some of them were implicated in fatty liver or post-transfusion NANB hepatitis.</description><subject>HBV carrier</subject><subject>seroconversion</subject><issn>0451-4203</issn><issn>1881-3593</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><recordid>eNo9kN1KAzEQhYMoWGrvfIA8gNFkk81uLrXUHyh4Yb1e0uykje5ulmSrrE9v2mphmHNgvhmGg9A1o7eZyou7T939-GRTiTM0YWXJCM8VP0cTKnJGREb5JZrF6NaUZrKgSmUTtFr6bkMGCC22vmn8N9n1-G3Y1SP2Fptt8J0zeAu9HtzgIn7AXy7sIjY6BAchHijf9robMbR940eAeIUurG4izP50it4fF6v5M1m-Pr3M75fEZDITRIqSF7UQYq0KyXOp6lrodVKwVouy4IZpYCx9S21dG7AlSGsp19xKkXPgU3RzvGuCjzGArfrgWh3GitFqH0p1CCXZVCLhiyP-EQe9gROsw-BMA0eYKbnfrfh_E6e52epQQcd_ASa8b9E</recordid><startdate>1988</startdate><enddate>1988</enddate><creator>SHIMA, Toshihide</creator><creator>SETO, Yoshifumi</creator><creator>SAKAMOTO, Yoshikuni</creator><creator>NAKAJIMA, Toshikazu</creator><creator>NAKASHIMA, Toshiaki</creator><creator>OKUNO, Tadao</creator><creator>TAKINO, Tatsuro</creator><creator>KOTANI, Mutsumi</creator><general>The Japan Society of Hepatology</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>1988</creationdate><title>Long-term follow-up Study of chronic hepatitis B virus carriers of company employees</title><author>SHIMA, Toshihide ; SETO, Yoshifumi ; SAKAMOTO, Yoshikuni ; NAKAJIMA, Toshikazu ; NAKASHIMA, Toshiaki ; OKUNO, Tadao ; TAKINO, Tatsuro ; KOTANI, Mutsumi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2624-64837d444b9763569dd4ab569effa4873c1ae110020fddcef8e6ff03a3f6453e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; jpn</language><creationdate>1988</creationdate><topic>HBV carrier</topic><topic>seroconversion</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SHIMA, Toshihide</creatorcontrib><creatorcontrib>SETO, Yoshifumi</creatorcontrib><creatorcontrib>SAKAMOTO, Yoshikuni</creatorcontrib><creatorcontrib>NAKAJIMA, Toshikazu</creatorcontrib><creatorcontrib>NAKASHIMA, Toshiaki</creatorcontrib><creatorcontrib>OKUNO, Tadao</creatorcontrib><creatorcontrib>TAKINO, Tatsuro</creatorcontrib><creatorcontrib>KOTANI, Mutsumi</creatorcontrib><collection>CrossRef</collection><jtitle>Kanzo</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SHIMA, Toshihide</au><au>SETO, Yoshifumi</au><au>SAKAMOTO, Yoshikuni</au><au>NAKAJIMA, Toshikazu</au><au>NAKASHIMA, Toshiaki</au><au>OKUNO, Tadao</au><au>TAKINO, Tatsuro</au><au>KOTANI, Mutsumi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-term follow-up Study of chronic hepatitis B virus carriers of company employees</atitle><jtitle>Kanzo</jtitle><addtitle>Kanzo</addtitle><date>1988</date><risdate>1988</risdate><volume>29</volume><issue>3</issue><spage>294</spage><epage>300</epage><pages>294-300</pages><issn>0451-4203</issn><eissn>1881-3593</eissn><abstract>Chronic hepatitis B virus carriers (HBV carriers) of company employees have been studied. The incidence of HBV carriers was 986 (1.17%) of 84, 456 company employees, of whom 157 (15.9%) had elevated GPT levels. The male and young HVB carriers had higher incidence of the elevated GPT level. Of 808 HBV carriers who were followed up during about 6 years, 280 were HBeAg-positive and 528 negative at the initial examination. Of 280 HBeAg-positive carriers, 39 became seronegative (SN) and 20 were seroconverted to anti-HBe (SC). Serum GPT was elevated in all the cases before SN or SC developed and since then, returned to the normal level in most of the cases. Of carriers with persistently positive HBeAg, HBeAg titer was higher in the normal GPT carrier (4.88±1.30) than in the elevated GPT carrier (4.14±1.42). Of carriers with persistently positive anti-HBe, persistently elevated GPT values had been noted in 25 (6%). Some of them were implicated in fatty liver or post-transfusion NANB hepatitis.</abstract><pub>The Japan Society of Hepatology</pub><doi>10.2957/kanzo.29.294</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0451-4203 |
| ispartof | Kanzo, 1988/03/25, Vol.29(3), pp.294-300 |
| issn | 0451-4203 1881-3593 |
| language | eng ; jpn |
| recordid | cdi_crossref_primary_10_2957_kanzo_29_294 |
| source | J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese |
| subjects | HBV carrier seroconversion |
| title | Long-term follow-up Study of chronic hepatitis B virus carriers of company employees |
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