Thrombocytopenia and its Severity in Plasmodium Vivax Positive Patients
Background: Plasmodium vivax, one of the four species of human malaria parasites, is responsible for a considerable portion of malaria cases. While P. vivax is often considered less severe than Plasmodium falciparum, it is not without its complications. Thrombocytopenia is a common hematological com...
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Veröffentlicht in: | Annals of Punjab Medical College 2023-12, Vol.17 (4), p.488-492 |
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description | Background: Plasmodium vivax, one of the four species of human malaria parasites, is responsible for a considerable portion of malaria cases. While P. vivax is often considered less severe than Plasmodium falciparum, it is not without its complications. Thrombocytopenia is a common hematological complication associated with malaria infections, including those caused by P. vivax. Objective: To evaluate the severity of thrombocytopenia and relationship between thrombocytopenia and demographic factors, such as age and gender, in Plasmodium vivax positive patients. Study Design: Cross sectional study. Settings: Medicine OPD of Liaquat University of Medical and Health Sciences / Jamshoro and Muhammad Medical College, Mirpur Khas Pakistan. Duration: Six months from May 2022 to October 2022. Methods: Individuals aged over 12 years of either gender with a confirmed diagnosis of Plasmodium vivax were included. A single blood sample was collected from each participant for platelet count analysis, and demographic details and platelet counts were recorded using standardized data collection forms. Thrombocytopenia was defined as a platelet count below a predetermined threshold (e.g., |
doi_str_mv | 10.29054/apmc/2023.1256 |
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While P. vivax is often considered less severe than Plasmodium falciparum, it is not without its complications. Thrombocytopenia is a common hematological complication associated with malaria infections, including those caused by P. vivax. Objective: To evaluate the severity of thrombocytopenia and relationship between thrombocytopenia and demographic factors, such as age and gender, in Plasmodium vivax positive patients. Study Design: Cross sectional study. Settings: Medicine OPD of Liaquat University of Medical and Health Sciences / Jamshoro and Muhammad Medical College, Mirpur Khas Pakistan. Duration: Six months from May 2022 to October 2022. Methods: Individuals aged over 12 years of either gender with a confirmed diagnosis of Plasmodium vivax were included. A single blood sample was collected from each participant for platelet count analysis, and demographic details and platelet counts were recorded using standardized data collection forms. Thrombocytopenia was defined as a platelet count below a predetermined threshold (e.g., <150,000 platelets/μL). All the information was collected via study proforma and SPSS version 26 was used for the analysis. Results: The participants had a mean age of 29.07 years. 122 individuals (61.3%) were male, and 77 individuals (38.7%) were female. Thrombocytopenia was highly prevalent in patients with a positive diagnosis of Plasmodium vivax, with a frequency of 83.4%. Among the affected individuals, 18.6% had mild thrombocytopenia, 38.2% had moderate thrombocytopenia, and 25.6% were observed with severe thrombocytopenia. According to the thrombocytopenia and its severity based on age and gender the p-values of 0.069 and 0.656 indicates no significant association of age and gender with thrombocytopenia severity. Conclusion: Study revealed a significant frequency of moderate to severe thrombocytopenia in individuals diagnosed with Plasmodium vivax infection and tends to be of moderate to severe intensity, without significant correlation of age and gender.</description><identifier>ISSN: 2077-9151</identifier><identifier>EISSN: 2077-9143</identifier><identifier>DOI: 10.29054/apmc/2023.1256</identifier><language>eng</language><ispartof>Annals of Punjab Medical College, 2023-12, Vol.17 (4), p.488-492</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,860,27901,27902</link.rule.ids></links><search><creatorcontrib>Shah, Mujtaba</creatorcontrib><creatorcontrib>Rani, Shabnam</creatorcontrib><creatorcontrib>Kumari, Komal</creatorcontrib><creatorcontrib>Memon, Nadeem</creatorcontrib><creatorcontrib>Memon, Zaheer Husain</creatorcontrib><creatorcontrib>Kumar, Rutesh</creatorcontrib><title>Thrombocytopenia and its Severity in Plasmodium Vivax Positive Patients</title><title>Annals of Punjab Medical College</title><description>Background: Plasmodium vivax, one of the four species of human malaria parasites, is responsible for a considerable portion of malaria cases. While P. vivax is often considered less severe than Plasmodium falciparum, it is not without its complications. Thrombocytopenia is a common hematological complication associated with malaria infections, including those caused by P. vivax. Objective: To evaluate the severity of thrombocytopenia and relationship between thrombocytopenia and demographic factors, such as age and gender, in Plasmodium vivax positive patients. Study Design: Cross sectional study. Settings: Medicine OPD of Liaquat University of Medical and Health Sciences / Jamshoro and Muhammad Medical College, Mirpur Khas Pakistan. Duration: Six months from May 2022 to October 2022. Methods: Individuals aged over 12 years of either gender with a confirmed diagnosis of Plasmodium vivax were included. A single blood sample was collected from each participant for platelet count analysis, and demographic details and platelet counts were recorded using standardized data collection forms. Thrombocytopenia was defined as a platelet count below a predetermined threshold (e.g., <150,000 platelets/μL). All the information was collected via study proforma and SPSS version 26 was used for the analysis. Results: The participants had a mean age of 29.07 years. 122 individuals (61.3%) were male, and 77 individuals (38.7%) were female. Thrombocytopenia was highly prevalent in patients with a positive diagnosis of Plasmodium vivax, with a frequency of 83.4%. Among the affected individuals, 18.6% had mild thrombocytopenia, 38.2% had moderate thrombocytopenia, and 25.6% were observed with severe thrombocytopenia. According to the thrombocytopenia and its severity based on age and gender the p-values of 0.069 and 0.656 indicates no significant association of age and gender with thrombocytopenia severity. Conclusion: Study revealed a significant frequency of moderate to severe thrombocytopenia in individuals diagnosed with Plasmodium vivax infection and tends to be of moderate to severe intensity, without significant correlation of age and gender.</description><issn>2077-9151</issn><issn>2077-9143</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNqVzj0LwjAUheEgCoo6u-YPaG9Sa8ksfowFxTXEGvGKaUpuLPbfS0Xcnc67HHgYmwlYSAXZMjG1KxMJMl0Ima16bCQhz-dKLNP-rzMxZFOiOwBIpSBP1Yjtjrfg3dmXbfS1rdBwU104RuIH29iAseVY8eJhyPkLPh0_YWNevPCEERvLCxPRVpEmbHA1D7LT745Zst0c1_t5GTxRsFddB3QmtFqA_pB1R9YdWXfk9P_HGyM5Sr0</recordid><startdate>20231231</startdate><enddate>20231231</enddate><creator>Shah, Mujtaba</creator><creator>Rani, Shabnam</creator><creator>Kumari, Komal</creator><creator>Memon, Nadeem</creator><creator>Memon, Zaheer Husain</creator><creator>Kumar, Rutesh</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20231231</creationdate><title>Thrombocytopenia and its Severity in Plasmodium Vivax Positive Patients</title><author>Shah, Mujtaba ; Rani, Shabnam ; Kumari, Komal ; Memon, Nadeem ; Memon, Zaheer Husain ; Kumar, Rutesh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-crossref_primary_10_29054_apmc_2023_12563</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shah, Mujtaba</creatorcontrib><creatorcontrib>Rani, Shabnam</creatorcontrib><creatorcontrib>Kumari, Komal</creatorcontrib><creatorcontrib>Memon, Nadeem</creatorcontrib><creatorcontrib>Memon, Zaheer Husain</creatorcontrib><creatorcontrib>Kumar, Rutesh</creatorcontrib><collection>CrossRef</collection><jtitle>Annals of Punjab Medical College</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shah, Mujtaba</au><au>Rani, Shabnam</au><au>Kumari, Komal</au><au>Memon, Nadeem</au><au>Memon, Zaheer Husain</au><au>Kumar, Rutesh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Thrombocytopenia and its Severity in Plasmodium Vivax Positive Patients</atitle><jtitle>Annals of Punjab Medical College</jtitle><date>2023-12-31</date><risdate>2023</risdate><volume>17</volume><issue>4</issue><spage>488</spage><epage>492</epage><pages>488-492</pages><issn>2077-9151</issn><eissn>2077-9143</eissn><abstract>Background: Plasmodium vivax, one of the four species of human malaria parasites, is responsible for a considerable portion of malaria cases. While P. vivax is often considered less severe than Plasmodium falciparum, it is not without its complications. Thrombocytopenia is a common hematological complication associated with malaria infections, including those caused by P. vivax. Objective: To evaluate the severity of thrombocytopenia and relationship between thrombocytopenia and demographic factors, such as age and gender, in Plasmodium vivax positive patients. Study Design: Cross sectional study. Settings: Medicine OPD of Liaquat University of Medical and Health Sciences / Jamshoro and Muhammad Medical College, Mirpur Khas Pakistan. Duration: Six months from May 2022 to October 2022. Methods: Individuals aged over 12 years of either gender with a confirmed diagnosis of Plasmodium vivax were included. A single blood sample was collected from each participant for platelet count analysis, and demographic details and platelet counts were recorded using standardized data collection forms. Thrombocytopenia was defined as a platelet count below a predetermined threshold (e.g., <150,000 platelets/μL). All the information was collected via study proforma and SPSS version 26 was used for the analysis. Results: The participants had a mean age of 29.07 years. 122 individuals (61.3%) were male, and 77 individuals (38.7%) were female. Thrombocytopenia was highly prevalent in patients with a positive diagnosis of Plasmodium vivax, with a frequency of 83.4%. Among the affected individuals, 18.6% had mild thrombocytopenia, 38.2% had moderate thrombocytopenia, and 25.6% were observed with severe thrombocytopenia. According to the thrombocytopenia and its severity based on age and gender the p-values of 0.069 and 0.656 indicates no significant association of age and gender with thrombocytopenia severity. Conclusion: Study revealed a significant frequency of moderate to severe thrombocytopenia in individuals diagnosed with Plasmodium vivax infection and tends to be of moderate to severe intensity, without significant correlation of age and gender.</abstract><doi>10.29054/apmc/2023.1256</doi></addata></record> |
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title | Thrombocytopenia and its Severity in Plasmodium Vivax Positive Patients |
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