Pharmacological cancer research using cancer cell line-derived xenograft (CDX) mouse models

A cell line-derived xenograft（CDX）model, prepared by transplanting human cancer cell line into mice, has been used in pharmacological cancer research for more than half a century. Even now, CDX models are adopted to evaluate pharmacological characteristics of various therapeutic modalities, includin...

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Veröffentlicht in:	Drug Delivery System 2024/07/25, Vol.39(3), pp.192-200
Hauptverfasser:	Tsumura, Ryo, Takashima, Hiroki
Format:	Artikel
Sprache:	eng ; jpn
Schlagworte:	Animal models antibody therapeutics Cancer Cancer research Cell culture Cell line-derived xenograft model Drug screening Immunodeficiency immunodeficient mice Medical research Microenvironments Nucleic acids pharmacological research Pharmacology Tumor microenvironment Tumors Xenografts Xenotransplantation
Online-Zugang:	Volltext
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