Prevalence of markers of celiac disease in Colombian children with diabetes mellitus type 1

Although the association between diabetes mellitus type 1 (T1DM) and celiac disease (CD) is well established; there are only a few studies that focus on South American children, haplotypes and their possible associations. To determine the prevalence of CD markers in a group of children with T1DM and...

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Veröffentlicht in:Colombia medica (Cali, Colombia) Colombia), 2018-12, Vol.49 (4), p.273-279
Hauptverfasser: Velasco-Benítez, Carlos Alberto, Ruíz-Extremera, Ángeles, Matallana-Rhoades, Audrey Mary, Giraldo-Lora, Sandra Carolina, Ortíz-Rivera, Claudia Jimena
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Sprache:eng
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Zusammenfassung:Although the association between diabetes mellitus type 1 (T1DM) and celiac disease (CD) is well established; there are only a few studies that focus on South American children, haplotypes and their possible associations. To determine the prevalence of CD markers in a group of children with T1DM and to analyze the associated clinical, immunological and genetic manifestations. A prevalence study focusing on children with T1DM who were assessed based on variables including sociodemographics, anthropometric information, disease characteristics, laboratory results and family medical history. In partitipants a positive tTG2 (Ig A anti-transglutaminase), a duodenal biopsy and genotype were performed. The proportion of children with T1DM and CD was estimated (CI 95%). Determinations of central tendency, univariate and bivariate analysis, were also performed;
ISSN:0120-8322
1657-9534
DOI:10.25100/cm.v49i4.3650