Effectiveness the pharmaceutical care in diabetic patients

Objective: To determine the effectiveness of pharmaceutical care to improve control of type-2 diabetes mellitus. Methods: We carried out pharmacotherapeutical intervention during 19 months on patients with type-2 diabetes mellitus who were affiliate members of the contributive regime of the General...

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Veröffentlicht in:Colombia médica (Cali, Colombia) Colombia), 2011-01, Vol.42 (1), p.72-80
Hauptverfasser: Machado-Alba, Jorge E, Torres-Rodríguez, Sandra, Vallejos-Narváez, Alvaro
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Torres-Rodríguez, Sandra
Vallejos-Narváez, Alvaro
description Objective: To determine the effectiveness of pharmaceutical care to improve control of type-2 diabetes mellitus. Methods: We carried out pharmacotherapeutical intervention during 19 months on patients with type-2 diabetes mellitus who were affiliate members of the contributive regime of the General System for Healthcare and Social Security in Bogotá and Cartagena. Through an interview and evaluation of medical records, we obtained information about antidiabetic medications used, doses, other medications, along with Hemoglobin A1c level, arterial pressure, serum low-density lipoprotein cholesterol level, nephropathy screening, retinal screening, foot exams in the last year and problems associated with medication use by means of the DADER method Negative Outcomes Associated with Medication (NOM). Results: The study had a sample of 143 patients (64 intervened and 79 controls) with female predominance (67.1% and 53.1%, respectively), mean age of 63.9±11.2 years. The patients in both groups were taking an average of 6.0±2.7 medications. Initial HbA1c mean was 7.7% and 7.8%, without improvement by the end of the study (7.4% for those intervened and 7.8% for the control group). Hypertension (81.1%) and dyslipidemia (62.9%) were the most important comorbidities. About 50.4% of NOM were of effectiveness, follows 31.3% of necessity. The mean cost per patient in controls was 1.4 greater than for the intervened group. Conclusions: Increased effectiveness of the antidiabetic therapy was not demonstrated in patients intervened with pharmacotherapeutical monitoring, but we did obtain a reduction in healthcare costs. Objetivo: Determinar la efectividad del seguimiento farmacoterapéutico para mejorar el control de los pacientes diabéticos tipo 2. Métodos: Se realizó intervención farmacoterapéutica durante 19 meses a pacientes con diabetes mellitus tipo 2, afiliados al régimen contributivo del Sistema General de Seguridad Social en Salud en Bogotá y Cartagena. Mediante entrevista y revisión de la historia clínica, se obtuvo información sobre medicamentos antidiabéticos utilizados, dosis, comedicación, resultados en último año de HbA1c, tensión arterial, perfil lipídico, albuminuria, examen oftalmológico, valoración de pies y los Resultados Negativos Asociados con la Medicación (RNM) y se siguió la metodología DADER. Resultados: Participaron 143 pacientes, 64 intervenidos y 79 controles, con predominio de mujeres (67.1% y 53.1%, respectivamente), promedio de edad 63.9±11.2 a
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Methods: We carried out pharmacotherapeutical intervention during 19 months on patients with type-2 diabetes mellitus who were affiliate members of the contributive regime of the General System for Healthcare and Social Security in Bogotá and Cartagena. Through an interview and evaluation of medical records, we obtained information about antidiabetic medications used, doses, other medications, along with Hemoglobin A1c level, arterial pressure, serum low-density lipoprotein cholesterol level, nephropathy screening, retinal screening, foot exams in the last year and problems associated with medication use by means of the DADER method Negative Outcomes Associated with Medication (NOM). Results: The study had a sample of 143 patients (64 intervened and 79 controls) with female predominance (67.1% and 53.1%, respectively), mean age of 63.9±11.2 years. The patients in both groups were taking an average of 6.0±2.7 medications. Initial HbA1c mean was 7.7% and 7.8%, without improvement by the end of the study (7.4% for those intervened and 7.8% for the control group). Hypertension (81.1%) and dyslipidemia (62.9%) were the most important comorbidities. About 50.4% of NOM were of effectiveness, follows 31.3% of necessity. The mean cost per patient in controls was 1.4 greater than for the intervened group. Conclusions: Increased effectiveness of the antidiabetic therapy was not demonstrated in patients intervened with pharmacotherapeutical monitoring, but we did obtain a reduction in healthcare costs. Objetivo: Determinar la efectividad del seguimiento farmacoterapéutico para mejorar el control de los pacientes diabéticos tipo 2. Métodos: Se realizó intervención farmacoterapéutica durante 19 meses a pacientes con diabetes mellitus tipo 2, afiliados al régimen contributivo del Sistema General de Seguridad Social en Salud en Bogotá y Cartagena. Mediante entrevista y revisión de la historia clínica, se obtuvo información sobre medicamentos antidiabéticos utilizados, dosis, comedicación, resultados en último año de HbA1c, tensión arterial, perfil lipídico, albuminuria, examen oftalmológico, valoración de pies y los Resultados Negativos Asociados con la Medicación (RNM) y se siguió la metodología DADER. Resultados: Participaron 143 pacientes, 64 intervenidos y 79 controles, con predominio de mujeres (67.1% y 53.1%, respectivamente), promedio de edad 63.9±11.2 años. Los pacientes de ambos grupos tomaban en promedio 6.0±2.7 medicamentos. La HbA1c inicial tuvo un promedio de 7.7% y 7.8% y al finalizar el estudio los valores fueron de 7.4% y 7.8%, respectivamente en cada grupo. El 50.4% de los RNM fueron de efectividad, seguido de 31.3% de necesidad. En la visita inicial y final la recomendación farmacéutica fue aceptada y el problema de salud resuelto en 72 casos (42.9% de RNM) y en 46 casos (38.3% de RNM), respectivamente. El cociente medio del costo por paciente en el grupo control fue 1.4 veces mayor que en el intervenido. Discusión: No se demostró aumento en la efectividad de la terapia antidiabética en pacientes intervenidos con seguimiento farmacoterapéutico, pero se consiguió una reducción en costos de la atención sanitaria.</description><identifier>ISSN: 0120-8322</identifier><identifier>EISSN: 1657-9534</identifier><identifier>DOI: 10.25100/cm.v42i1.753</identifier><language>eng</language><publisher>Universidad del Valle - Facultad de Salud</publisher><subject>Agentes hipoglucémicos ; Colombia ; Diabetes mellitus ; Glucosylated hemoglobin A ; Hemoglobina A glucosilada ; Hypoglycemic agents ; Pharmaceutical services ; Servicios farmacéuticos</subject><ispartof>Colombia médica (Cali, Colombia), 2011-01, Vol.42 (1), p.72-80</ispartof><rights>Copyright 2011 Colombia Médica.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b354t-9db53509a582dc204cd5d312fc139438e3a2ca569cebfd3d9bc6ad6c1d9a3de63</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27907,27908,79177</link.rule.ids></links><search><creatorcontrib>Machado-Alba, Jorge E</creatorcontrib><creatorcontrib>Torres-Rodríguez, Sandra</creatorcontrib><creatorcontrib>Vallejos-Narváez, Alvaro</creatorcontrib><title>Effectiveness the pharmaceutical care in diabetic patients</title><title>Colombia médica (Cali, Colombia)</title><description>Objective: To determine the effectiveness of pharmaceutical care to improve control of type-2 diabetes mellitus. Methods: We carried out pharmacotherapeutical intervention during 19 months on patients with type-2 diabetes mellitus who were affiliate members of the contributive regime of the General System for Healthcare and Social Security in Bogotá and Cartagena. Through an interview and evaluation of medical records, we obtained information about antidiabetic medications used, doses, other medications, along with Hemoglobin A1c level, arterial pressure, serum low-density lipoprotein cholesterol level, nephropathy screening, retinal screening, foot exams in the last year and problems associated with medication use by means of the DADER method Negative Outcomes Associated with Medication (NOM). Results: The study had a sample of 143 patients (64 intervened and 79 controls) with female predominance (67.1% and 53.1%, respectively), mean age of 63.9±11.2 years. The patients in both groups were taking an average of 6.0±2.7 medications. Initial HbA1c mean was 7.7% and 7.8%, without improvement by the end of the study (7.4% for those intervened and 7.8% for the control group). Hypertension (81.1%) and dyslipidemia (62.9%) were the most important comorbidities. About 50.4% of NOM were of effectiveness, follows 31.3% of necessity. The mean cost per patient in controls was 1.4 greater than for the intervened group. Conclusions: Increased effectiveness of the antidiabetic therapy was not demonstrated in patients intervened with pharmacotherapeutical monitoring, but we did obtain a reduction in healthcare costs. Objetivo: Determinar la efectividad del seguimiento farmacoterapéutico para mejorar el control de los pacientes diabéticos tipo 2. Métodos: Se realizó intervención farmacoterapéutica durante 19 meses a pacientes con diabetes mellitus tipo 2, afiliados al régimen contributivo del Sistema General de Seguridad Social en Salud en Bogotá y Cartagena. Mediante entrevista y revisión de la historia clínica, se obtuvo información sobre medicamentos antidiabéticos utilizados, dosis, comedicación, resultados en último año de HbA1c, tensión arterial, perfil lipídico, albuminuria, examen oftalmológico, valoración de pies y los Resultados Negativos Asociados con la Medicación (RNM) y se siguió la metodología DADER. Resultados: Participaron 143 pacientes, 64 intervenidos y 79 controles, con predominio de mujeres (67.1% y 53.1%, respectivamente), promedio de edad 63.9±11.2 años. Los pacientes de ambos grupos tomaban en promedio 6.0±2.7 medicamentos. La HbA1c inicial tuvo un promedio de 7.7% y 7.8% y al finalizar el estudio los valores fueron de 7.4% y 7.8%, respectivamente en cada grupo. El 50.4% de los RNM fueron de efectividad, seguido de 31.3% de necesidad. En la visita inicial y final la recomendación farmacéutica fue aceptada y el problema de salud resuelto en 72 casos (42.9% de RNM) y en 46 casos (38.3% de RNM), respectivamente. El cociente medio del costo por paciente en el grupo control fue 1.4 veces mayor que en el intervenido. Discusión: No se demostró aumento en la efectividad de la terapia antidiabética en pacientes intervenidos con seguimiento farmacoterapéutico, pero se consiguió una reducción en costos de la atención sanitaria.</description><subject>Agentes hipoglucémicos</subject><subject>Colombia</subject><subject>Diabetes mellitus</subject><subject>Glucosylated hemoglobin A</subject><subject>Hemoglobina A glucosilada</subject><subject>Hypoglycemic agents</subject><subject>Pharmaceutical services</subject><subject>Servicios farmacéuticos</subject><issn>0120-8322</issn><issn>1657-9534</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>RBI</sourceid><recordid>eNo9j1FLwzAUhYMoWKePvvcPtCa5Tdf4JmM6YeCLPofbm1sWabuR1IH_3rKpcODA4ePAJ8S9kqU2SsoHGspjpYMqlwYuRKZqsyysgepSZFJpWTSg9bW4SelTSm2rRmbicd11TFM48sgp5dOO88MO44DEX1Mg7HPCyHkYcx-w5XnKDzgFHqd0K6467BPf_fZCfDyv31ebYvv28rp62hYtmGoqrG8NGGnRNNqTlhV540HpjhTYChoG1ISmtsRt58Hblmr0NSlvETzXsBDF-ZfiPqXInTvEMGD8dkq6k7ijwZ3E3Sw-8-WZb8O-DyP_4xQDur8x0hylpJLwA6nqXkE</recordid><startdate>20110101</startdate><enddate>20110101</enddate><creator>Machado-Alba, Jorge E</creator><creator>Torres-Rodríguez, Sandra</creator><creator>Vallejos-Narváez, Alvaro</creator><general>Universidad del Valle - Facultad de Salud</general><scope>RBI</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20110101</creationdate><title>Effectiveness the pharmaceutical care in diabetic patients</title><author>Machado-Alba, Jorge E ; Torres-Rodríguez, Sandra ; Vallejos-Narváez, Alvaro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b354t-9db53509a582dc204cd5d312fc139438e3a2ca569cebfd3d9bc6ad6c1d9a3de63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Agentes hipoglucémicos</topic><topic>Colombia</topic><topic>Diabetes mellitus</topic><topic>Glucosylated hemoglobin A</topic><topic>Hemoglobina A glucosilada</topic><topic>Hypoglycemic agents</topic><topic>Pharmaceutical services</topic><topic>Servicios farmacéuticos</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Machado-Alba, Jorge E</creatorcontrib><creatorcontrib>Torres-Rodríguez, Sandra</creatorcontrib><creatorcontrib>Vallejos-Narváez, Alvaro</creatorcontrib><collection>Bioline International</collection><collection>CrossRef</collection><jtitle>Colombia médica (Cali, Colombia)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Machado-Alba, Jorge E</au><au>Torres-Rodríguez, Sandra</au><au>Vallejos-Narváez, Alvaro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effectiveness the pharmaceutical care in diabetic patients</atitle><jtitle>Colombia médica (Cali, Colombia)</jtitle><date>2011-01-01</date><risdate>2011</risdate><volume>42</volume><issue>1</issue><spage>72</spage><epage>80</epage><pages>72-80</pages><issn>0120-8322</issn><eissn>1657-9534</eissn><abstract>Objective: To determine the effectiveness of pharmaceutical care to improve control of type-2 diabetes mellitus. Methods: We carried out pharmacotherapeutical intervention during 19 months on patients with type-2 diabetes mellitus who were affiliate members of the contributive regime of the General System for Healthcare and Social Security in Bogotá and Cartagena. Through an interview and evaluation of medical records, we obtained information about antidiabetic medications used, doses, other medications, along with Hemoglobin A1c level, arterial pressure, serum low-density lipoprotein cholesterol level, nephropathy screening, retinal screening, foot exams in the last year and problems associated with medication use by means of the DADER method Negative Outcomes Associated with Medication (NOM). Results: The study had a sample of 143 patients (64 intervened and 79 controls) with female predominance (67.1% and 53.1%, respectively), mean age of 63.9±11.2 years. The patients in both groups were taking an average of 6.0±2.7 medications. Initial HbA1c mean was 7.7% and 7.8%, without improvement by the end of the study (7.4% for those intervened and 7.8% for the control group). Hypertension (81.1%) and dyslipidemia (62.9%) were the most important comorbidities. About 50.4% of NOM were of effectiveness, follows 31.3% of necessity. The mean cost per patient in controls was 1.4 greater than for the intervened group. Conclusions: Increased effectiveness of the antidiabetic therapy was not demonstrated in patients intervened with pharmacotherapeutical monitoring, but we did obtain a reduction in healthcare costs. Objetivo: Determinar la efectividad del seguimiento farmacoterapéutico para mejorar el control de los pacientes diabéticos tipo 2. Métodos: Se realizó intervención farmacoterapéutica durante 19 meses a pacientes con diabetes mellitus tipo 2, afiliados al régimen contributivo del Sistema General de Seguridad Social en Salud en Bogotá y Cartagena. Mediante entrevista y revisión de la historia clínica, se obtuvo información sobre medicamentos antidiabéticos utilizados, dosis, comedicación, resultados en último año de HbA1c, tensión arterial, perfil lipídico, albuminuria, examen oftalmológico, valoración de pies y los Resultados Negativos Asociados con la Medicación (RNM) y se siguió la metodología DADER. Resultados: Participaron 143 pacientes, 64 intervenidos y 79 controles, con predominio de mujeres (67.1% y 53.1%, respectivamente), promedio de edad 63.9±11.2 años. Los pacientes de ambos grupos tomaban en promedio 6.0±2.7 medicamentos. La HbA1c inicial tuvo un promedio de 7.7% y 7.8% y al finalizar el estudio los valores fueron de 7.4% y 7.8%, respectivamente en cada grupo. El 50.4% de los RNM fueron de efectividad, seguido de 31.3% de necesidad. En la visita inicial y final la recomendación farmacéutica fue aceptada y el problema de salud resuelto en 72 casos (42.9% de RNM) y en 46 casos (38.3% de RNM), respectivamente. El cociente medio del costo por paciente en el grupo control fue 1.4 veces mayor que en el intervenido. Discusión: No se demostró aumento en la efectividad de la terapia antidiabética en pacientes intervenidos con seguimiento farmacoterapéutico, pero se consiguió una reducción en costos de la atención sanitaria.</abstract><pub>Universidad del Valle - Facultad de Salud</pub><doi>10.25100/cm.v42i1.753</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
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source Bioline International; EZB-FREE-00999 freely available EZB journals
subjects Agentes hipoglucémicos
Colombia
Diabetes mellitus
Glucosylated hemoglobin A
Hemoglobina A glucosilada
Hypoglycemic agents
Pharmaceutical services
Servicios farmacéuticos
title Effectiveness the pharmaceutical care in diabetic patients
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