The Effects of Nonenzymatic Glycation on Human α2-Plasmin Inhibitor in Vitro

We studied the effects of nonenzymatic glycation on human α2-plasmin inhibitor (α2-PI) in vitro. Purified human α2-PI (14.9μM/l) was incubated with glucose (55.5mM/l) at 37°C for 4 days. α2-PI was significantly glycated, and then the activity of glycated α2-PI decreased, while the levels of α2-PI an...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Japanese Journal of Thrombosis and Hemostasis 1994/06/01, Vol.5(3), pp.182-189
Hauptverfasser:	YAMASHITA, Tsutomu, FUJII, Seiji, INOUE, Kaori, HATAKEDA, Noriko, KOBAYASHI, Emi, MATSUOKA, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	active site binding site (ABS) kringle binding site (KBS) lysine binding site I (LBS I) nonenzymatic glycation α2-Plasmin inhibitor
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!