In Vivo Response of Osteoblast-like and Odontoblast-like Cells in Intraperitoneal Diffusion Chamber
Preliminary analysis of cells before using them in tissue engineering is mandatory. Thus, to clarify the behavior of cells in an appropriate experimental model, we evaluated the characteristic of MDPC-23 cells and KUSA/A1 cells in vitro and in vivo seeded in diffusion chamber. Our results indicated...
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Veröffentlicht in: | Journal of Hard Tissue Biology 2005, Vol.14(2), pp.294-295 |
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container_title | Journal of Hard Tissue Biology |
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creator | Rodriguez, Andrea Paola Tsujigiwa, Hidetsugu Nagatsuka, Hitoshi Ichikawa, Kazuo Minonishi, Atsuhisa Liliana, Missana Qin, C. L. Nagai, Noriyuki |
description | Preliminary analysis of cells before using them in tissue engineering is mandatory. Thus, to clarify the behavior of cells in an appropriate experimental model, we evaluated the characteristic of MDPC-23 cells and KUSA/A1 cells in vitro and in vivo seeded in diffusion chamber. Our results indicated that KUSA/A1 cells differentiated into osteoblast-like cells and induced bone tissue inside the chamber. Whereas, MDPC-23 cells were odontoblast-like cells but with low ability to induce dentin formation. This study suggests that MDPC-23 cells are special cells, which possess morphological and functional character of odontoblast-like cells, expressing DSPP only in vivo with low capacity to induce mineralized dentin matrix. |
doi_str_mv | 10.2485/jhtb.14.294 |
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This study suggests that MDPC-23 cells are special cells, which possess morphological and functional character of odontoblast-like cells, expressing DSPP only in vivo with low capacity to induce mineralized dentin matrix.</description><subject>diffusion chamber</subject><subject>KUSA/A1 cells</subject><subject>MDPC-23 cells</subject><issn>1341-7649</issn><issn>1880-828X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><recordid>eNpNkE1LAzEQhoMoWKsn_0DusjWfu9mbsn4VhIKoeFuym4lN3SYliYL_3i2V6mVmeOeZOTwInVMyY0LJy9UydzMqZqwWB2hClSKFYurtcJy5oEVVivoYnaS0IqSkVV1PUD_3-NV9BfwEaRN8AhwsXqQMoRt0ysXgPgBrb_DCBJ__hw0MQ8LO47nPUW8guhw86AHfOGs_kwseN0u97iCeoiOrhwRnv32KXu5un5uH4nFxP2-uH4ueq1oUVoAspTGkMlQILZioGWe044Z3WksYE2Yl5xWpFSXaViUnJWfSWCVpTxmfoovd3z6GlCLYdhPdWsfvlpJ266fd-mmpaEc_I321o1cp63fYszpm1w_wx-7KeLJf9UsdW_D8B3BJcMk</recordid><startdate>2005</startdate><enddate>2005</enddate><creator>Rodriguez, Andrea Paola</creator><creator>Tsujigiwa, Hidetsugu</creator><creator>Nagatsuka, Hitoshi</creator><creator>Ichikawa, Kazuo</creator><creator>Minonishi, Atsuhisa</creator><creator>Liliana, Missana</creator><creator>Qin, C. 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subjects | diffusion chamber KUSA/A1 cells MDPC-23 cells |
title | In Vivo Response of Osteoblast-like and Odontoblast-like Cells in Intraperitoneal Diffusion Chamber |
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