Maidenhair tree (Ginkgo Bilobae) leaf extraction products in the light of Biopharmaceutics Classification System (BCS) requirements and medium of diversified polarity (εM)

Model maidenhair tree (Ginkgo bilobae) leaf extracts were created basing on medium of diversified polarity (ε ). Chromatographic analysis was performed with the HPLC method, with the so-called dry residue remaining after evaporating the dissolving agent from saturated aqueous solutions and from 0.1...

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Veröffentlicht in:Herba polonica 2014-03, Vol.60 (1), p.18-28
Hauptverfasser: Nowak, Elżbieta, Nachajski, Michał Jakub, Zgoda, Marian Mikołaj
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description Model maidenhair tree (Ginkgo bilobae) leaf extracts were created basing on medium of diversified polarity (ε ). Chromatographic analysis was performed with the HPLC method, with the so-called dry residue remaining after evaporating the dissolving agent from saturated aqueous solutions and from 0.1 mol HCl. Viscosity measure and surface activity estimations were conducted on phase boundary. Then, basic values of viscosity ([η], M ) and hydrodynamic values (Ro, Robs., Ω) were calculated. Moreover, reference quercetin and rutin (rutoside) were used to mark the conversion contents of flavonoids in produced extracts with the UV method. Wytworzono modelowe ekstrakty z liści miłorzębu japońskiego (Ginkgo bilobae), korzystając z medium o zróżnicowanej polarności (ε ). Przeprowadzono analizę chromatograficzną metodą HPLC tzw. suchej pozostałości uzyskanej po odparowaniu rozpuszczalnika z nasyconych wodnych roztworów i z 0,1 mol HCl. Przeprowadzono pomiary lepkościowe i aktywności powierzchniowej na granicy faz. Wyliczono podstawowe wielkości lepkościowe ([η], M ) i hydrodynamiczne (Ro, Robs., Ω). Korzystając z referencyjnej kwercetyny i rutyny (rutozydu) przeliczeniową metodą UV oznaczono również zawartość flawonoidów w wytworzonych ekstraktach.
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subjects dry extract
Ginkgo bilobae
lepkość
polarity
polarność
suchy ekstrakt
viscosity
title Maidenhair tree (Ginkgo Bilobae) leaf extraction products in the light of Biopharmaceutics Classification System (BCS) requirements and medium of diversified polarity (εM)
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