Thrombin Regulates Soluble fms-Like Tyrosine Kinase-1 (sFlt-1) Expression in First Trimester Decidua

The primary placental defect in preeclampsia is shallow trophoblast invasion of the decidua leading to incomplete vascular transformation and inadequate uteroplacental perfusion. Soluble fms-like tyrosine kinase-1 (sFlt-1) seems to interfere with these events by inhibiting local angiogenesis and/or...

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Veröffentlicht in:	The American journal of pathology 2007, Vol.170 (4), p.1398-1405
Hauptverfasser:	Lockwood, Charles J, Toti, Paolo, Arcuri, Felice, Norwitz, Errol, Funai, Edmund F, Huang, Se-Te J, Buchwalder, Lynn F, Krikun, Graciela, Schatz, Frederick
Format:	Artikel
Sprache:	eng
Schlagworte:	Pathology
Online-Zugang:	Volltext
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