DNA Repair Enzyme Ogg1 Regulates Hepatic Insulin Resistance in High-Fat Diet-Fed Obese Mice

Mitochondrial DNA (mtDNA) damage has been implicated in the development of insulin resistance. The mtDNA is highly specialized and encodes for proteins essential for energy metabolism. Also, mtDNA damage heightens mitochondrial oxidative stress, which is very critical for insulin resistance. OGG1 (8...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2018-07, Vol.67 (Supplement_1)
Hauptverfasser:	YUZEFOVYCH, LARYSA, SCHULER, MICHELE, NOH, HYE LIM, SUK, SUJIN, KIM, JASON K., RACHEK, LYUDMILA
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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