Hepatic Effects of Inhaled Plutonium Dioxide in Beagles

The effects of inhaled ^{238}{\rm PuO}{}_{2}$ deposited in the liver of dogs were studied in beagles exposed to initial lung depositions ranging from 5.7 to 2979.7 Bq/g lung. Approximately 20% of the initial lung deposition was translocated to the liver by 1500 days after exposure. Life-span observa...

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Veröffentlicht in:	Radiation Research 1995-10, Vol.144 (1), p.73-81
Hauptverfasser:	Weller, R. E., Buschbom, R. L., Dagle, G. E., Ragan, H. A., Park, J. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Alanine Transaminase - blood Animals Aspartate Aminotransferases - blood BEAGLES Biochemistry Biological and medical sciences Biological effects of radiation BIOLOGICAL LOCALIZATION BIOLOGICAL RADIATION EFFECTS BIOLOGY AND MEDICINE, APPLIED STUDIES Bones Dogs Dosage Dose-Response Relationship, Radiation ENZYME ACTIVITY Enzymes Female Fundamental and applied biological sciences. Psychology INHALATION Ionizing radiations LIVER Liver - pathology Liver - physiology Liver - radiation effects Liver Neoplasms, Experimental - etiology Lungs Male NEOPLASMS Plutonium Plutonium - toxicity PLUTONIUM DIOXIDE Radiation dosage REGRESSION ANALYSIS SKELETON Tissues, organs and organisms biophysics Tumors
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