Radiation Mutagenesis: The Initial DNA Lesions Responsible

This paper is an attempt to initiate a discussion about the causes of radiation-induced mutagenesis. It considers the evidence for the involvement of singly base-damaged sites as sources of this mutagenesis. Several sets of published data are examined: These include endogenous levels of oxidized bas...

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Veröffentlicht in:	Radiation Research 1995-06, Vol.142 (3), p.362-368
1. Verfasser:	Ward, J. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biological effects of radiation BIOLOGY AND MEDICINE, APPLIED STUDIES Commentary DNA DNA - radiation effects DNA Damage Dose-Response Relationship, Radiation Earthquake damage Fundamental and applied biological sciences. Psychology Genetic mutation Humans Hydrogen Ionizing radiation IONIZING RADIATIONS K562 cells Kidney cells LET Linear Energy Transfer MUTAGENESIS Mutagenesis - radiation effects Peroxides Radiation damage Radiation dosage RADIATION INJURIES RADIOINDUCTION Rats STRAND BREAKS Tissues, organs and organisms biophysics
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