DNA Repair Kinetics in Mammalian Cells Following Split-Dose Irradiation

The in situ DNA repair kinetics in intracerebral 9L tumor cells and cerebellar neurons following the second of two 1250- or 2500-rad doses separated by various times have been measured using alkaline sucrose gradients in zonal rotors. For both doses and all times employed, both cell types exhibited...

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Veröffentlicht in:	Radiat. Res.; (United States) 1984-05, Vol.98 (2), p.242-253
Hauptverfasser:	Wierowski, James V., Thomas, Rolland R., Wheeler, Kenneth T.
Format:	Artikel
Sprache:	eng
Schlagworte:	560111 > Radiation Effects on Biochemicals-- In Vitro-- (-1987) ALKALI METAL ISOTOPES ANIMAL CELLS Animals BETA DECAY RADIOISOTOPES BETA-MINUS DECAY RADIOISOTOPES Biological and medical sciences BIOLOGICAL EFFECTS Biological effects of radiation BIOLOGICAL RADIATION EFFECTS BIOLOGICAL RECOVERY BIOLOGICAL REPAIR Brain Neoplasms - genetics Brain Neoplasms - radiotherapy CARBON 14 COMPOUNDS Cerebellum - radiation effects CESIUM 137 CESIUM ISOTOPES Cesium Radioisotopes CHO cells Chromatin DATA DNA DNA damage DNA Repair DNA, Neoplasm - radiation effects ENZYMES ESTERASES EXPERIMENTAL DATA FRACTIONATED IRRADIATION Fundamental and applied biological sciences. Psychology Gamma Rays HYDROLASES INFORMATION Ionizing radiations IRRADIATION ISOTOPES KINETICS LABELLED COMPOUNDS Lesions Male Neoplasm Transplantation NERVE CELLS Neurons NUCLEASES NUCLEI NUCLEIC ACIDS NUMERICAL DATA ODD-EVEN NUCLEI ORGANIC COMPOUNDS PHOSPHODIESTERASES Radiation damage RADIATION EFFECTS Radiation Genetics RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIOISOTOPES Rats Rats, Inbred F344 RECOVERY REPAIR SOMATIC CELLS Time Factors Tissues, organs and organisms biophysics TUMOR CELLS Tumors YEARS LIVING RADIOISOTOPES 560121 > Radiation Effects on Cells-- External Source-- (-1987)
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