In Vivo Cytotoxicity of Misonidazole and Hyperthermia in a Transplanted Mouse Mammary Tumor

The cytotoxicity of misonidazole (miso) in vivo in unclamped tumors at hyperthermic temperatures, and in clamped tumors at hypothermic, euthermic, and hyperthermic temperatures has been examined. No cytotoxicity, measured as increased tumor control, was observed in unclamped tumors heated 30 min aft...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Radiation research 1983-12, Vol.96 (3), p.628-634
Hauptverfasser:	Lehman, Christopher M., Stewart, J. Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cancer Cytotoxicity Dosage Dose response relationship Drug Evaluation, Preclinical Female Hyperthermia Hyperthermia, Induced Hypoxia Induced hyperthermia. Cryotherapy Male Mammary Neoplasms, Experimental - therapy Medical sciences Mice Mice, Inbred C3H Miso Misonidazole - therapeutic use Misonidazole - toxicity Neoplasm Transplantation Nitroimidazoles - toxicity Temperature Temperature control Temperature dependence Time Factors Treatment with physical agents Treatment. General aspects Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!