Postirradiation Hemopoietic Repopulation and Stromal Cell Viability

To evaluate some of the microenvironmental conditions necessary to support hemopoiesis, the right femurs of mice were X-irradiated. Femoral radioiron uptake in the right femur after 1000 rad fell to 20 ± 2% of the control (mean ± 1 SEM) at 3 days and returned to 67 ± 5% by 6 months. Erythroblast cou...

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Veröffentlicht in:	Radiat. Res.; (United States) 1977-07, Vol.71 (1), p.214-224
Hauptverfasser:	Werts, E. D., Johnson, M. J., DeGowin, R. L.
Format:	Artikel
Sprache:	eng
Schlagworte:	560152 - Radiation Effects on Animals- Animals ANIMAL CELLS ANIMALS BETA DECAY RADIOISOTOPES BETA-MINUS DECAY RADIOISOTOPES BIOLOGICAL EFFECTS BIOLOGICAL RADIATION EFFECTS BIOLOGICAL RECOVERY BIOLOGICAL REGENERATION Blood Cell Count BLOOD FORMATION BODY Bone marrow Bone Marrow - metabolism Bone Marrow - radiation effects BONE MARROW CELLS CONNECTIVE TISSUE CELLS Cultured cells DAYS LIVING RADIOISOTOPES Dose-Response Relationship, Radiation DOSE-RESPONSE RELATIONSHIPS ELECTROMAGNETIC RADIATION Erythroblasts Erythropoiesis - radiation effects EVEN-ODD NUCLEI Female FEMUR Guinea Pigs Hematopoiesis - radiation effects INTERMEDIATE MASS NUCLEI IONIZING RADIATIONS IRON 59 IRON ISOTOPES Iron Radioisotopes Irradiation ISOTOPES Legs MAMMALS MICE NUCLEI ORGANS Radiation dosage RADIATION EFFECTS RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIATIONS RADIOISOTOPES RECOVERY RODENTS SKELETON SOMATIC CELLS Spleen - metabolism Stem cells Stromal cells Time Factors UPTAKE VERTEBRATES X RADIATION
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