Detection of Pulmonary Irradiation Injury by Determining Plasma Lactic Dehydrogenase (LDH) Activity

Under short-acting anesthesia, the right hemithorax of 11 dogs was irradiated with 800 and 1000-1200 rads (60 Co), and blood samples were taken sequentially for 36 hr. Three other dogs were anesthetized but not irradiated, for controls. We assayed the activities of plasma lactic dehydrogenase (LDH)...

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Veröffentlicht in:	Radiat. Res., v. 57, no. 2, pp. 311-318 v. 57, no. 2, pp. 311-318, 1974-02, Vol.57 (2), p.311-318
Hauptverfasser:	Bloor, Colin M., Leroy, Elie P., Friedman, Paul J., Sobel, Burton E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals BIOLOGICAL RADIATION EFFECTS BLOOD Blood plasma CATALYSIS CHEST Cobalt Radioisotopes Dehydrogenases DOGS Dose-Response Relationship, Radiation DOSE-RESPONSE RELATIONSHIPS ENZYMES GAMMA RADIATION Irradiation ISOENZYMES L-Lactate Dehydrogenase - blood LACTATE DEHYDROGENASE- BIOCHEMICAL REACTION KINETICS Lactates Lung - pathology Lung - radiation effects Lung injury Lungs LUNGS- RADIATION INJURIES METABOLISM MORPHOLOGICAL CHANGES N48520 -Life Sciences-Radiation Effects on Animals- Vertebrates PHOTON BEAMS Physical trauma Pneumocytes Radiation damage Radiation Injuries, Experimental - blood Radiation Injuries, Experimental - pathology
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