Cytogenetic Investigation of Industrial Workers Occupationally Exposed to Gamma Rays
The incidence of chromosome aberrations has been studied in blood cells of 16 technicians occupationally exposed to gamma irradiation, 8 of whom had been irradiated with doses higher than allowed and the other 8 with smaller than allowed ones. The blood cell count of all subjects did not present abn...
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| Veröffentlicht in: | Radiat. Res. 47: No. 2, 562-70(Aug 1971) 562-70(Aug 1971), 1971-08, Vol.47 (2), p.562-570 |
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| container_title | Radiat. Res. 47: No. 2, 562-70(Aug 1971) |
| container_volume | 47 |
| creator | Popescu, H. I. Stefanescu, D. T. |
| description | The incidence of chromosome aberrations has been studied in blood cells of 16 technicians occupationally exposed to gamma irradiation, 8 of whom had been irradiated with doses higher than allowed and the other 8 with smaller than allowed ones. The blood cell count of all subjects did not present abnormalities at any of the periodical medical check-ups. Although the peripheral blood picture was normal, chromosome aberrations in 48-50-hour cultures of blood were detected. The incidence of chromosome aberrations, mainly fragments, distinctly differed (p < 0.001) from that of an equal number of controls. This incidence was also different (p < 0.001) between those who had received doses higher than permissible and the other ones. It should be emphasized that although the incidence of chromosome aberrations did not increase in step with the total accumulated dose, the aberrations can be found even as a result of small doses even though the usual hematological parameters were not modified. |
| doi_str_mv | 10.2307/3573261 |
| format | Article |
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I. ; Stefanescu, D. T.</creator><creatorcontrib>Popescu, H. I. ; Stefanescu, D. T. ; Inst. of Hygiene and Public Health, Bucharest. Inst. for Pathology and Medical Genetics, Bucharest</creatorcontrib><description>The incidence of chromosome aberrations has been studied in blood cells of 16 technicians occupationally exposed to gamma irradiation, 8 of whom had been irradiated with doses higher than allowed and the other 8 with smaller than allowed ones. The blood cell count of all subjects did not present abnormalities at any of the periodical medical check-ups. Although the peripheral blood picture was normal, chromosome aberrations in 48-50-hour cultures of blood were detected. The incidence of chromosome aberrations, mainly fragments, distinctly differed (p < 0.001) from that of an equal number of controls. This incidence was also different (p < 0.001) between those who had received doses higher than permissible and the other ones. It should be emphasized that although the incidence of chromosome aberrations did not increase in step with the total accumulated dose, the aberrations can be found even as a result of small doses even though the usual hematological parameters were not modified.</description><identifier>ISSN: 0033-7587</identifier><identifier>EISSN: 1938-5404</identifier><identifier>DOI: 10.2307/3573261</identifier><identifier>PMID: 5561944</identifier><language>eng</language><publisher>United States: Academic Press, Inc</publisher><subject>Adult ; Blood ; Blood Cell Count ; BLOOD CELLS ; Chromosome Aberrations ; CHROMOSOMES ; Chromosomes - radiation effects ; CHROMOSOMES/radioinduced aberrations in human blood cell, following occupational exposure ; Cytogenetics ; Dosimetry ; Environmental Exposure ; GAMMA RADIATION ; GAMMA RADIATION/effects on blood cell chromosomes of industrial personnel following occupational exposure ; Gamma rays ; Humans ; INDUSTRY ; Irradiation ; Lymphocytes ; MALFORMATIONS ; Middle Aged ; N28300 -Life Sciences-Genetics & Cytogenetics ; N28630 - Life Sciences-Radiation Effects on Animals-Man ; Occupational Diseases ; PERSONNEL/radioinduced chromosome aberrations in blood cells of industrial ; Radiation accidents ; Radiation dosage ; RADIATION EFFECTS ; Radiation Genetics ; Radiation Injuries - genetics</subject><ispartof>Radiat. Res. 47: No. 2, 562-70(Aug 1971), 1971-08, Vol.47 (2), p.562-570</ispartof><rights>Copyright 1971 Academic Press, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c332t-5dc6d075a41b1309b16b218e05ada9aa7c66d83e546ce89b39fd4f45d6a1063a3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/3573261$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/3573261$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,885,27924,27925,58017,58250</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5561944$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/4744689$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Popescu, H. I.</creatorcontrib><creatorcontrib>Stefanescu, D. T.</creatorcontrib><creatorcontrib>Inst. of Hygiene and Public Health, Bucharest. Inst. for Pathology and Medical Genetics, Bucharest</creatorcontrib><title>Cytogenetic Investigation of Industrial Workers Occupationally Exposed to Gamma Rays</title><title>Radiat. Res. 47: No. 2, 562-70(Aug 1971)</title><addtitle>Radiat Res</addtitle><description>The incidence of chromosome aberrations has been studied in blood cells of 16 technicians occupationally exposed to gamma irradiation, 8 of whom had been irradiated with doses higher than allowed and the other 8 with smaller than allowed ones. The blood cell count of all subjects did not present abnormalities at any of the periodical medical check-ups. Although the peripheral blood picture was normal, chromosome aberrations in 48-50-hour cultures of blood were detected. The incidence of chromosome aberrations, mainly fragments, distinctly differed (p < 0.001) from that of an equal number of controls. This incidence was also different (p < 0.001) between those who had received doses higher than permissible and the other ones. It should be emphasized that although the incidence of chromosome aberrations did not increase in step with the total accumulated dose, the aberrations can be found even as a result of small doses even though the usual hematological parameters were not modified.</description><subject>Adult</subject><subject>Blood</subject><subject>Blood Cell Count</subject><subject>BLOOD CELLS</subject><subject>Chromosome Aberrations</subject><subject>CHROMOSOMES</subject><subject>Chromosomes - radiation effects</subject><subject>CHROMOSOMES/radioinduced aberrations in human blood cell, following occupational exposure</subject><subject>Cytogenetics</subject><subject>Dosimetry</subject><subject>Environmental Exposure</subject><subject>GAMMA RADIATION</subject><subject>GAMMA RADIATION/effects on blood cell chromosomes of industrial personnel following occupational exposure</subject><subject>Gamma rays</subject><subject>Humans</subject><subject>INDUSTRY</subject><subject>Irradiation</subject><subject>Lymphocytes</subject><subject>MALFORMATIONS</subject><subject>Middle Aged</subject><subject>N28300 -Life Sciences-Genetics & Cytogenetics</subject><subject>N28630 - Life Sciences-Radiation Effects on Animals-Man</subject><subject>Occupational Diseases</subject><subject>PERSONNEL/radioinduced chromosome aberrations in blood cells of industrial</subject><subject>Radiation accidents</subject><subject>Radiation dosage</subject><subject>RADIATION EFFECTS</subject><subject>Radiation Genetics</subject><subject>Radiation Injuries - genetics</subject><issn>0033-7587</issn><issn>1938-5404</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1971</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kF1LwzAUhoMoc07xFwhBBK-qSfPVXMqYUxgMZOJlSZN0drZNSTKx_95qh3deHc55H14ODwCXGN2lBIl7wgRJOT4CUyxJljCK6DGYIkRIIlgmTsFZCDs07JjLCZgwxrGkdAo28z66rW1trDR8bj9tiNVWxcq10JXDwexD9JWq4ZvzH9YHuNZ63_0Cqq57uPjqXLAGRgeXqmkUfFF9OAcnpaqDvTjMGXh9XGzmT8lqvXyeP6wSTUgaE2Y0N0gwRXGBCZIF5kWKM4uYMkoqJTTnJiOWUa5tJgsiS0NLygxXGHGiyAxcj71u-DoPuopWv2vXtlbHnApKeSYH6HaEtHcheFvmna8a5fsco_zHXX5wN5BXI9nti8aaP-4ga8hvxnwXovP_1nwD8eB0MQ</recordid><startdate>197108</startdate><enddate>197108</enddate><creator>Popescu, H. I.</creator><creator>Stefanescu, D. T.</creator><general>Academic Press, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>197108</creationdate><title>Cytogenetic Investigation of Industrial Workers Occupationally Exposed to Gamma Rays</title><author>Popescu, H. I. ; Stefanescu, D. T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c332t-5dc6d075a41b1309b16b218e05ada9aa7c66d83e546ce89b39fd4f45d6a1063a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1971</creationdate><topic>Adult</topic><topic>Blood</topic><topic>Blood Cell Count</topic><topic>BLOOD CELLS</topic><topic>Chromosome Aberrations</topic><topic>CHROMOSOMES</topic><topic>Chromosomes - radiation effects</topic><topic>CHROMOSOMES/radioinduced aberrations in human blood cell, following occupational exposure</topic><topic>Cytogenetics</topic><topic>Dosimetry</topic><topic>Environmental Exposure</topic><topic>GAMMA RADIATION</topic><topic>GAMMA RADIATION/effects on blood cell chromosomes of industrial personnel following occupational exposure</topic><topic>Gamma rays</topic><topic>Humans</topic><topic>INDUSTRY</topic><topic>Irradiation</topic><topic>Lymphocytes</topic><topic>MALFORMATIONS</topic><topic>Middle Aged</topic><topic>N28300 -Life Sciences-Genetics & Cytogenetics</topic><topic>N28630 - Life Sciences-Radiation Effects on Animals-Man</topic><topic>Occupational Diseases</topic><topic>PERSONNEL/radioinduced chromosome aberrations in blood cells of industrial</topic><topic>Radiation accidents</topic><topic>Radiation dosage</topic><topic>RADIATION EFFECTS</topic><topic>Radiation Genetics</topic><topic>Radiation Injuries - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Popescu, H. I.</creatorcontrib><creatorcontrib>Stefanescu, D. T.</creatorcontrib><creatorcontrib>Inst. of Hygiene and Public Health, Bucharest. Inst. for Pathology and Medical Genetics, Bucharest</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>Radiat. Res. 47: No. 2, 562-70(Aug 1971)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Popescu, H. I.</au><au>Stefanescu, D. T.</au><aucorp>Inst. of Hygiene and Public Health, Bucharest. Inst. for Pathology and Medical Genetics, Bucharest</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cytogenetic Investigation of Industrial Workers Occupationally Exposed to Gamma Rays</atitle><jtitle>Radiat. Res. 47: No. 2, 562-70(Aug 1971)</jtitle><addtitle>Radiat Res</addtitle><date>1971-08</date><risdate>1971</risdate><volume>47</volume><issue>2</issue><spage>562</spage><epage>570</epage><pages>562-570</pages><issn>0033-7587</issn><eissn>1938-5404</eissn><abstract>The incidence of chromosome aberrations has been studied in blood cells of 16 technicians occupationally exposed to gamma irradiation, 8 of whom had been irradiated with doses higher than allowed and the other 8 with smaller than allowed ones. The blood cell count of all subjects did not present abnormalities at any of the periodical medical check-ups. Although the peripheral blood picture was normal, chromosome aberrations in 48-50-hour cultures of blood were detected. The incidence of chromosome aberrations, mainly fragments, distinctly differed (p < 0.001) from that of an equal number of controls. This incidence was also different (p < 0.001) between those who had received doses higher than permissible and the other ones. It should be emphasized that although the incidence of chromosome aberrations did not increase in step with the total accumulated dose, the aberrations can be found even as a result of small doses even though the usual hematological parameters were not modified.</abstract><cop>United States</cop><pub>Academic Press, Inc</pub><pmid>5561944</pmid><doi>10.2307/3573261</doi><tpages>9</tpages></addata></record> |
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| identifier | ISSN: 0033-7587 |
| ispartof | Radiat. Res. 47: No. 2, 562-70(Aug 1971), 1971-08, Vol.47 (2), p.562-570 |
| issn | 0033-7587 1938-5404 |
| language | eng |
| recordid | cdi_crossref_primary_10_2307_3573261 |
| source | MEDLINE; JSTOR Archive Collection A-Z Listing |
| subjects | Adult Blood Blood Cell Count BLOOD CELLS Chromosome Aberrations CHROMOSOMES Chromosomes - radiation effects CHROMOSOMES/radioinduced aberrations in human blood cell, following occupational exposure Cytogenetics Dosimetry Environmental Exposure GAMMA RADIATION GAMMA RADIATION/effects on blood cell chromosomes of industrial personnel following occupational exposure Gamma rays Humans INDUSTRY Irradiation Lymphocytes MALFORMATIONS Middle Aged N28300 -Life Sciences-Genetics & Cytogenetics N28630 - Life Sciences-Radiation Effects on Animals-Man Occupational Diseases PERSONNEL/radioinduced chromosome aberrations in blood cells of industrial Radiation accidents Radiation dosage RADIATION EFFECTS Radiation Genetics Radiation Injuries - genetics |
| title | Cytogenetic Investigation of Industrial Workers Occupationally Exposed to Gamma Rays |
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