Modulation of nickel-induced bursting with 4-aminopyridine in leech retzius nerve cells

Paroxysmal depolarization shift has been identified as a characteristic feature of the cellular basis of epilepsy. On Na+-dependent bursting, 1 mmol/l 4-aminopyridine (4-AP) produced a two-phase effect - a significant depolarization accompanied by an increase in the frequency of bursting, followed b...

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Veröffentlicht in:Archives of biological sciences 2010, Vol.62 (4), p.1035-1045
Hauptverfasser: Pathak, Dhruba, Lopicic, S., Bratic-Stanojevic, Marija, Pavlovic, D., Andjus, P.R., Nedeljkov, V.
Format: Artikel
Sprache:eng
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