The association between HLA-B15:02 and phenytoin-induced severe cutaneous adverse reactions: a meta-analysis

Phenytoin (PHT) is a common anticonvulsant agent known for inducing severe cutaneous adverse reactions (SCARs). as a risk factor of PHT-induced SCARs was reported in numerous studies with inconsistent results. This meta-analysis aimed to establish pooling evidence of this association. Pooled odds ra...

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Veröffentlicht in:	Pharmacogenomics 2022-01, Vol.23 (1), p.49-59
Hauptverfasser:	Phung, Thanh Huong, Cong Duong, Khanh Ngoc, Junio Gloria, Mac Ardy, Nguyen, Thien Khac
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticonvulsants - adverse effects HLA-B15 Antigen - genetics Humans Phenytoin - adverse effects Stevens-Johnson Syndrome - etiology Stevens-Johnson Syndrome - genetics
Online-Zugang:	Volltext
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