Inebilizumab for treatment of neuromyelitis optica spectrum disorder

Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disease characterized by recurrent optic neuritis and transverse myelitis often resulting in severe disability. Anti-AQP4-immunoglobulin G (IgG) is a pathogenic product of CD19-positive plasma cells found in most, but not all, indiv...

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Veröffentlicht in:	Neurodegenerative disease management 2021-10, Vol.11 (5), p.341-352
Hauptverfasser:	J Tullman, Mark, Zabeti, Aram, Vuocolo, Scott, Dinh, Quinn
Format:	Artikel
Sprache:	eng
Schlagworte:	anti-aquaporin-4–immunoglobulin G anti-CD19 monoclonal antibody Antibodies, Monoclonal Antibodies, Monoclonal, Humanized - therapeutic use Aquaporin 4 CD19-positive B-cell clinical trial expanded disability status scale Humans N-MOmentum Neuromyelitis Optica - drug therapy optic neuritis transverse myelitis
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