PULSATILE DRUG DELIVERY SYSTEMS THE NOVEL APPROACH
Oral pulsatile drug delivery systems (PDDS) are intended to induce programmable lag phases before a quick and quantifiable, repeated, or prolonged medication release. As a result, they are gaining popularity due to their inherent suitability for achieving chronotherapeutic goals, which have just bee...
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Veröffentlicht in: | International journal of pharmacy and pharmaceutical sciences 2024-02, p.1-11 |
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creator | BODKE, VISHAL TEKADE, BHARAT W. BADEKAR, RUCHITA PHALAK, SWAPNIL D. KALE, MOHAN |
description | Oral pulsatile drug delivery systems (PDDS) are intended to induce programmable lag phases before a quick and quantifiable, repeated, or prolonged medication release. As a result, they are gaining popularity due to their inherent suitability for achieving chronotherapeutic goals, which have just been highlighted concerning several prevalent chronic illnesses characterized by typical night or early-morning recurring symptoms (e. g. bronchial asthma, heart attack, rheumatoid arthritis, early-morningawakening). Furthermore, time-based colonic release is possible when pulsatile delivery devices are correctly modified to overcome unexpected gastric emptying and give delay periods that roughly match the small intestine transit time. Oral pulsatile administration is accomplished using several release platforms, including reservoir, capsular, and osmotic devices.
The current review article addressed the topics that followed: the reason pulsatile drug delivery systems have been invented; diseases for which pulsatile release is necessary; classification, advantages and disadvantages; methods used in the current systems; the situation nowadays and its potential for the future; recent advancements, and especially, the previous five to ten years of research on pulsatile drug delivery conducted by researchers using a variety of drugs for a variety of diseases. |
doi_str_mv | 10.22159/ijpps.2024v16i2.49960 |
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The current review article addressed the topics that followed: the reason pulsatile drug delivery systems have been invented; diseases for which pulsatile release is necessary; classification, advantages and disadvantages; methods used in the current systems; the situation nowadays and its potential for the future; recent advancements, and especially, the previous five to ten years of research on pulsatile drug delivery conducted by researchers using a variety of drugs for a variety of diseases.</description><identifier>ISSN: 2656-0097</identifier><identifier>EISSN: 0975-1491</identifier><identifier>DOI: 10.22159/ijpps.2024v16i2.49960</identifier><language>eng</language><ispartof>International journal of pharmacy and pharmaceutical sciences, 2024-02, p.1-11</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-crossref_primary_10_22159_ijpps_2024v16i2_499603</cites><orcidid>0009-0006-9342-0689 ; 0000-0002-5858-8287 ; 0009-0009-1689-2633</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27907,27908</link.rule.ids></links><search><creatorcontrib>BODKE, VISHAL</creatorcontrib><creatorcontrib>TEKADE, BHARAT W.</creatorcontrib><creatorcontrib>BADEKAR, RUCHITA</creatorcontrib><creatorcontrib>PHALAK, SWAPNIL D.</creatorcontrib><creatorcontrib>KALE, MOHAN</creatorcontrib><title>PULSATILE DRUG DELIVERY SYSTEMS THE NOVEL APPROACH</title><title>International journal of pharmacy and pharmaceutical sciences</title><description>Oral pulsatile drug delivery systems (PDDS) are intended to induce programmable lag phases before a quick and quantifiable, repeated, or prolonged medication release. As a result, they are gaining popularity due to their inherent suitability for achieving chronotherapeutic goals, which have just been highlighted concerning several prevalent chronic illnesses characterized by typical night or early-morning recurring symptoms (e. g. bronchial asthma, heart attack, rheumatoid arthritis, early-morningawakening). Furthermore, time-based colonic release is possible when pulsatile delivery devices are correctly modified to overcome unexpected gastric emptying and give delay periods that roughly match the small intestine transit time. Oral pulsatile administration is accomplished using several release platforms, including reservoir, capsular, and osmotic devices.
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title | PULSATILE DRUG DELIVERY SYSTEMS THE NOVEL APPROACH |
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