A SINGLE CASE REPORT ON HYPONATREMIA SEIZURE INDUCED BY ACETYLCHOLINESTERASE INHIBITORS

A SINGLE CASE REPORT ON HYPONATREMIA SEIZURE INDUCED BY ACETYLCHOLINESTERASE INHIBITORS

Donepezil and memantine are the acetylcholinesterase inhibitors most commonly used in clinical practice for the management of mild-moderate dementia in Alzheimer’s disease. Electrolyte abnormalities associated with the drugs are commonly encountered in daily clinical practice and often can lead to s...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:International journal of pharmacy and pharmaceutical sciences 2017-07, Vol.9 (7), p.165
Hauptverfasser: Shareef, J., Joseph, J., K., Adithi
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue 7
container_start_page 165
container_title International journal of pharmacy and pharmaceutical sciences
container_volume 9
creator Shareef, J.
Joseph, J.
K., Adithi
description Donepezil and memantine are the acetylcholinesterase inhibitors most commonly used in clinical practice for the management of mild-moderate dementia in Alzheimer’s disease. Electrolyte abnormalities associated with the drugs are commonly encountered in daily clinical practice and often can lead to seizures. Hyponatremia is an uncommon adverse effects of acetylcholinesterase inhibitors. Here we present a case on hyponatremia seizure due to the syndrome of inappropriate antidiuretic hormone (SIADH) caused by the acetylcholinesterase inhibitor donepezil and memantine as other likely causes were ruled out by appropriate investigations. The causality assessment needed to be done according to Naranjo algorithm was found to be ‘probable’ and the level of severity according to the Hartwig scale was ‘Level 5’.
doi_str_mv 10.22159/ijpps.2017v9i7.19057
format Article
fullrecord <record><control><sourceid>crossref</sourceid><recordid>TN_cdi_crossref_primary_10_22159_ijpps_2017v9i7_19057</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_22159_ijpps_2017v9i7_19057</sourcerecordid><originalsourceid>FETCH-LOGICAL-c987-349e7e6a1d4af556fba2888fa5707ec5e3047b82c02918cf405873be612cf4ea3</originalsourceid><addsrcrecordid>eNpNkNFKwzAYhYMoOOYeQcgLtCZp0ySXXRfXQG1GmyH1JqQ1hQ7F0YLg29tVBc_NOQfO_198ANxjFBKCqXgYTufzFBKE2acYWIgFouwKrJBgNMCxwNf_8i3YTNMJzYoRwShagecU1qrcFxJmaS1hJQ-6MlCXMG8OukxNJZ_UPJHq5VhJqMrdMZM7uG1gmknTFFmuC1XK2sjqcq7KXG2V0VV9B2569zb5za-vgXmUJsuDQu9VlhZBJzgLolh45hOHX2PXU5r0rSOc895RhpjvqI9QzFpOOkQE5l0fI8pZ1PoEk7l4F60B_XnbjR_TNPrensfh3Y1fFiO78LELH_vHxy58om_38lOP</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>A SINGLE CASE REPORT ON HYPONATREMIA SEIZURE INDUCED BY ACETYLCHOLINESTERASE INHIBITORS</title><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Shareef, J. ; Joseph, J. ; K., Adithi</creator><creatorcontrib>Shareef, J. ; Joseph, J. ; K., Adithi</creatorcontrib><description>Donepezil and memantine are the acetylcholinesterase inhibitors most commonly used in clinical practice for the management of mild-moderate dementia in Alzheimer’s disease. Electrolyte abnormalities associated with the drugs are commonly encountered in daily clinical practice and often can lead to seizures. Hyponatremia is an uncommon adverse effects of acetylcholinesterase inhibitors. Here we present a case on hyponatremia seizure due to the syndrome of inappropriate antidiuretic hormone (SIADH) caused by the acetylcholinesterase inhibitor donepezil and memantine as other likely causes were ruled out by appropriate investigations. The causality assessment needed to be done according to Naranjo algorithm was found to be ‘probable’ and the level of severity according to the Hartwig scale was ‘Level 5’.</description><identifier>ISSN: 0975-1491</identifier><identifier>EISSN: 0975-1491</identifier><identifier>DOI: 10.22159/ijpps.2017v9i7.19057</identifier><language>eng</language><ispartof>International journal of pharmacy and pharmaceutical sciences, 2017-07, Vol.9 (7), p.165</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c987-349e7e6a1d4af556fba2888fa5707ec5e3047b82c02918cf405873be612cf4ea3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Shareef, J.</creatorcontrib><creatorcontrib>Joseph, J.</creatorcontrib><creatorcontrib>K., Adithi</creatorcontrib><title>A SINGLE CASE REPORT ON HYPONATREMIA SEIZURE INDUCED BY ACETYLCHOLINESTERASE INHIBITORS</title><title>International journal of pharmacy and pharmaceutical sciences</title><description>Donepezil and memantine are the acetylcholinesterase inhibitors most commonly used in clinical practice for the management of mild-moderate dementia in Alzheimer’s disease. Electrolyte abnormalities associated with the drugs are commonly encountered in daily clinical practice and often can lead to seizures. Hyponatremia is an uncommon adverse effects of acetylcholinesterase inhibitors. Here we present a case on hyponatremia seizure due to the syndrome of inappropriate antidiuretic hormone (SIADH) caused by the acetylcholinesterase inhibitor donepezil and memantine as other likely causes were ruled out by appropriate investigations. The causality assessment needed to be done according to Naranjo algorithm was found to be ‘probable’ and the level of severity according to the Hartwig scale was ‘Level 5’.</description><issn>0975-1491</issn><issn>0975-1491</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNpNkNFKwzAYhYMoOOYeQcgLtCZp0ySXXRfXQG1GmyH1JqQ1hQ7F0YLg29tVBc_NOQfO_198ANxjFBKCqXgYTufzFBKE2acYWIgFouwKrJBgNMCxwNf_8i3YTNMJzYoRwShagecU1qrcFxJmaS1hJQ-6MlCXMG8OukxNJZ_UPJHq5VhJqMrdMZM7uG1gmknTFFmuC1XK2sjqcq7KXG2V0VV9B2569zb5za-vgXmUJsuDQu9VlhZBJzgLolh45hOHX2PXU5r0rSOc895RhpjvqI9QzFpOOkQE5l0fI8pZ1PoEk7l4F60B_XnbjR_TNPrensfh3Y1fFiO78LELH_vHxy58om_38lOP</recordid><startdate>20170701</startdate><enddate>20170701</enddate><creator>Shareef, J.</creator><creator>Joseph, J.</creator><creator>K., Adithi</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20170701</creationdate><title>A SINGLE CASE REPORT ON HYPONATREMIA SEIZURE INDUCED BY ACETYLCHOLINESTERASE INHIBITORS</title><author>Shareef, J. ; Joseph, J. ; K., Adithi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c987-349e7e6a1d4af556fba2888fa5707ec5e3047b82c02918cf405873be612cf4ea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Shareef, J.</creatorcontrib><creatorcontrib>Joseph, J.</creatorcontrib><creatorcontrib>K., Adithi</creatorcontrib><collection>CrossRef</collection><jtitle>International journal of pharmacy and pharmaceutical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shareef, J.</au><au>Joseph, J.</au><au>K., Adithi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A SINGLE CASE REPORT ON HYPONATREMIA SEIZURE INDUCED BY ACETYLCHOLINESTERASE INHIBITORS</atitle><jtitle>International journal of pharmacy and pharmaceutical sciences</jtitle><date>2017-07-01</date><risdate>2017</risdate><volume>9</volume><issue>7</issue><spage>165</spage><pages>165-</pages><issn>0975-1491</issn><eissn>0975-1491</eissn><abstract>Donepezil and memantine are the acetylcholinesterase inhibitors most commonly used in clinical practice for the management of mild-moderate dementia in Alzheimer’s disease. Electrolyte abnormalities associated with the drugs are commonly encountered in daily clinical practice and often can lead to seizures. Hyponatremia is an uncommon adverse effects of acetylcholinesterase inhibitors. Here we present a case on hyponatremia seizure due to the syndrome of inappropriate antidiuretic hormone (SIADH) caused by the acetylcholinesterase inhibitor donepezil and memantine as other likely causes were ruled out by appropriate investigations. The causality assessment needed to be done according to Naranjo algorithm was found to be ‘probable’ and the level of severity according to the Hartwig scale was ‘Level 5’.</abstract><doi>10.22159/ijpps.2017v9i7.19057</doi></addata></record>
fulltext fulltext
identifier ISSN: 0975-1491
ispartof International journal of pharmacy and pharmaceutical sciences, 2017-07, Vol.9 (7), p.165
issn 0975-1491
0975-1491
language eng
recordid cdi_crossref_primary_10_22159_ijpps_2017v9i7_19057
source EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
title A SINGLE CASE REPORT ON HYPONATREMIA SEIZURE INDUCED BY ACETYLCHOLINESTERASE INHIBITORS
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T21%3A54%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-crossref&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20SINGLE%20CASE%20REPORT%20ON%20HYPONATREMIA%20SEIZURE%20INDUCED%20BY%20ACETYLCHOLINESTERASE%20INHIBITORS&rft.jtitle=International%20journal%20of%20pharmacy%20and%20pharmaceutical%20sciences&rft.au=Shareef,%20J.&rft.date=2017-07-01&rft.volume=9&rft.issue=7&rft.spage=165&rft.pages=165-&rft.issn=0975-1491&rft.eissn=0975-1491&rft_id=info:doi/10.22159/ijpps.2017v9i7.19057&rft_dat=%3Ccrossref%3E10_22159_ijpps_2017v9i7_19057%3C/crossref%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true