ANTICANCER DRUGS AS PROSPECTIVE EFFLUX PUMP INHIBITORS FOR SALMONELLA TYPHI PRODUCE CONFLICTING RESULTS IN IN SILICO AND IN VITRO STUDIES

Objective: Anticancer drugs paclitaxel and vinblastine were tested for their potential as efflux pump inhibitors for Salmonella Typhi-based on in silico and in vitro studies.Methods: Three-dimensional protein models of AcrAB-TolC of Salmonella Typhi were generated by online server PHYRE-2. The quali...

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Veröffentlicht in:	International journal of pharmacy and pharmaceutical sciences 2016-12, Vol.8 (12), p.244
Hauptverfasser:	Gupta, Pranjali, Gautam, Pankaj, Rai, Nishant
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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