INHIBITION OF GASTRIC DEGRADATION OF OMEPRAZOLE USING A pH-SENSITIVE POLYMER AS A BINDER IN TABLET FORMULATION

Objective: This work was aimed at formulating omeprazole tablets using afzelia gum as a binder that is capable of inhibiting the gastric degradation of the drug. Methods: Afzelia gum at different concentrations of 0, 5, 10, 15, 20 and 30% was used as a binder to formulate omeprazole tablets. The tab...

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Veröffentlicht in:International journal of applied pharmaceutics 2021-09, p.331-335
Hauptverfasser: OLORUNSOLA, EMMANUEL O., E. UDOH, IMO, MAJEKODUNMI, STEPHEN O., ODIONG, INIOBONG J., EBONG, UWAKMFON O.
Format: Artikel
Sprache:eng
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