Chrysin: A Potential Antiandrogen Ligand to Mutated Androgen Receptors in Prostate Cancer

Androgen receptor mutations, particularly T877A and W741L, promote prostate cancer (PCa). The main therapies against PCa use androgen receptor (AR) antagonists, including Bicalutamide; but these drugs lose their effectiveness over time. Chrysin is a flavonoid with several biological activities, incl...

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Veröffentlicht in:	Current molecular pharmacology 2025-01, Vol.18
Hauptverfasser:	Carranza-Aranda, Ahtziri Socorro, Santerre, Anne, Segura-Cabrera, Aldo, Cárdenas-Vargas, Albertina, Martínez-Velázquez, Moisés, Hernández-Gutiérrez, Rodolfo, Herrera-Rodríguez, Sara Elisa
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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