Lung Cancer Complicated by Silicosis : A Clinical and Histopathological Study
A clinicopathological analysis was carried out on 16 cases of lung cancer complicated by silicosis, which were diagnosed from April 1975 to March 1983, and the results were discussed with a review of the literature. All of the patients were male, and a smoking habit with a Brinkman index of more tha...
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Veröffentlicht in: | Japanese Journal of Medicine 1985, Vol.24(1), pp.3-7 |
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creator | TASHIRO, Takayoshi NASU, Masaru GOTO, Jun ITOGA, Takashi NAGATO, Hiroshi |
description | A clinicopathological analysis was carried out on 16 cases of lung cancer complicated by silicosis, which were diagnosed from April 1975 to March 1983, and the results were discussed with a review of the literature. All of the patients were male, and a smoking habit with a Brinkman index of more than 500 was found in 14 of them (87.5%). Twelve cases (75.0%) had advanced tumors of clinical stages III and IV, suggesting that the early detection of lung cancer complicated by silicosis is difficult. Tumors were uniformly found in all lobes of the lung. Histological types were mainly epidermoid or undifferentiated carcinoma, with very few adenocarcinomas. Carcinogens from smoking seemed to be responsible for the carcinogenesis. Twocases were thought to be scar carcinomas. |
doi_str_mv | 10.2169/internalmedicine1962.24.3 |
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All of the patients were male, and a smoking habit with a Brinkman index of more than 500 was found in 14 of them (87.5%). Twelve cases (75.0%) had advanced tumors of clinical stages III and IV, suggesting that the early detection of lung cancer complicated by silicosis is difficult. Tumors were uniformly found in all lobes of the lung. Histological types were mainly epidermoid or undifferentiated carcinoma, with very few adenocarcinomas. Carcinogens from smoking seemed to be responsible for the carcinogenesis. 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All of the patients were male, and a smoking habit with a Brinkman index of more than 500 was found in 14 of them (87.5%). Twelve cases (75.0%) had advanced tumors of clinical stages III and IV, suggesting that the early detection of lung cancer complicated by silicosis is difficult. Tumors were uniformly found in all lobes of the lung. Histological types were mainly epidermoid or undifferentiated carcinoma, with very few adenocarcinomas. Carcinogens from smoking seemed to be responsible for the carcinogenesis. Twocases were thought to be scar carcinomas.</description><subject>Adult</subject><subject>Histopathology of lung cancer complicated by silicosis</subject><subject>Humans</subject><subject>Incidence of lung cancer</subject><subject>Lung - diagnostic imaging</subject><subject>Lung - pathology</subject><subject>Lung cancer</subject><subject>Lung Neoplasms - complications</subject><subject>Lung Neoplasms - diagnostic imaging</subject><subject>Lung Neoplasms - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Radiography</subject><subject>Silicosis</subject><subject>Silicosis - complications</subject><subject>Silicosis - diagnostic imaging</subject><subject>Smoking</subject><issn>0021-5120</issn><issn>1881-123X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kL1OwzAUhS0EKqXwCEjmAVJ87diN2aoIKFKBoSCxRY7jtK5SJ7LdoW9PIFUnWO7fd88ZDkJ3QKYUhLy3LhrvVLMzldXWGZCCTmk6ZWdoDFkGCVD2dY7GhFBIOFByia5C2BKSCprRERoxKWU_j9Hrcu_WOFdOG4_zdtc1VqtoKlwe8Mr2SxtswA94jvPGup41WLkKL2yIbafipm3a9e91FffV4Rpd1KoJ5ubYJ-jz6fEjXyTL9-eXfL5MNCcQk6yuiZBClkBASm4yLoExwme1FgY4V1JmFaMloRUYKIUu635gqch4OVNMsgmSg6_2bQje1EXn7U75QwGk-Emo-CuhgqYF67W3g7bblz09KY-R9Pxt4NsQ1dqcuPLR6sb86wxDYadHvVG-MI59A4HMg8Y</recordid><startdate>19850101</startdate><enddate>19850101</enddate><creator>TASHIRO, Takayoshi</creator><creator>NASU, Masaru</creator><creator>GOTO, Jun</creator><creator>ITOGA, Takashi</creator><creator>NAGATO, Hiroshi</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19850101</creationdate><title>Lung Cancer Complicated by Silicosis : A Clinical and Histopathological Study</title><author>TASHIRO, Takayoshi ; NASU, Masaru ; GOTO, Jun ; ITOGA, Takashi ; NAGATO, Hiroshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c501t-8ff06969b101995e859133057fc6e155a998d32b02d1e1b6cbfd1e34685b7a393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Adult</topic><topic>Histopathology of lung cancer complicated by silicosis</topic><topic>Humans</topic><topic>Incidence of lung cancer</topic><topic>Lung - diagnostic imaging</topic><topic>Lung - pathology</topic><topic>Lung cancer</topic><topic>Lung Neoplasms - complications</topic><topic>Lung Neoplasms - diagnostic imaging</topic><topic>Lung Neoplasms - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Radiography</topic><topic>Silicosis</topic><topic>Silicosis - complications</topic><topic>Silicosis - diagnostic imaging</topic><topic>Smoking</topic><toplevel>online_resources</toplevel><creatorcontrib>TASHIRO, Takayoshi</creatorcontrib><creatorcontrib>NASU, Masaru</creatorcontrib><creatorcontrib>GOTO, Jun</creatorcontrib><creatorcontrib>ITOGA, Takashi</creatorcontrib><creatorcontrib>NAGATO, Hiroshi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Japanese Journal of Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>TASHIRO, Takayoshi</au><au>NASU, Masaru</au><au>GOTO, Jun</au><au>ITOGA, Takashi</au><au>NAGATO, Hiroshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lung Cancer Complicated by Silicosis : A Clinical and Histopathological Study</atitle><jtitle>Japanese Journal of Medicine</jtitle><addtitle>Japanese Journal of Medicine</addtitle><date>1985-01-01</date><risdate>1985</risdate><volume>24</volume><issue>1</issue><spage>3</spage><epage>7</epage><pages>3-7</pages><issn>0021-5120</issn><eissn>1881-123X</eissn><abstract>A clinicopathological analysis was carried out on 16 cases of lung cancer complicated by silicosis, which were diagnosed from April 1975 to March 1983, and the results were discussed with a review of the literature. All of the patients were male, and a smoking habit with a Brinkman index of more than 500 was found in 14 of them (87.5%). Twelve cases (75.0%) had advanced tumors of clinical stages III and IV, suggesting that the early detection of lung cancer complicated by silicosis is difficult. Tumors were uniformly found in all lobes of the lung. Histological types were mainly epidermoid or undifferentiated carcinoma, with very few adenocarcinomas. Carcinogens from smoking seemed to be responsible for the carcinogenesis. Twocases were thought to be scar carcinomas.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>3999462</pmid><doi>10.2169/internalmedicine1962.24.3</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Histopathology of lung cancer complicated by silicosis Humans Incidence of lung cancer Lung - diagnostic imaging Lung - pathology Lung cancer Lung Neoplasms - complications Lung Neoplasms - diagnostic imaging Lung Neoplasms - pathology Male Middle Aged Radiography Silicosis Silicosis - complications Silicosis - diagnostic imaging Smoking |
title | Lung Cancer Complicated by Silicosis : A Clinical and Histopathological Study |
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