Anatomical-physiological approaches in pharmacokinetics and pharmacodynamics

Use of an anatomical-physiological approach allows an investigator an alternative to regarding the whole body as a 'black box' producing biofluid specimens for drug assay, and then blindly applying a formula-driven mathematical approach to determine the pharmacokinetics and pharmacodynamic...

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Veröffentlicht in:	Clinical pharmacokinetics 2001, Vol.40 (10), p.707-722
1. Verfasser:	MATHER, Laurence E
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics, Opioid - pharmacokinetics Analgesics, Opioid - pharmacology Anesthetics, Local - pharmacokinetics Anesthetics, Local - pharmacology Animals Biological and medical sciences General pharmacology Humans Liver - metabolism Liver - physiology Medical sciences Models, Biological Pharmacokinetics Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology Pharmacology. Drug treatments Stereoisomerism Tissue Distribution
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