Vitamin supplementation therapy in the elderly

Vitamin supplementation in large dosages is increasingly common in the older population. Often, such supplementation is used in an attempt to improve an individual's health status. There have been claims that the effects of vitamins halt the normal aging process or prevent and cure disease. How...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Drugs & aging 1997-12, Vol.11 (6), p.433-449
Hauptverfasser: THURMAN, J. E, MOORADIAN, A. D
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 449
container_issue 6
container_start_page 433
container_title Drugs & aging
container_volume 11
creator THURMAN, J. E
MOORADIAN, A. D
description Vitamin supplementation in large dosages is increasingly common in the older population. Often, such supplementation is used in an attempt to improve an individual's health status. There have been claims that the effects of vitamins halt the normal aging process or prevent and cure disease. However, several recent studies have failed to demonstrate the efficacy of vitamin supplementation in preventing several types of cancer. In moderate dosages, supplementation with vitamin E (tocopherols) shows promise as a lipid antioxidant, and may reduce the risk of coronary heart disease. However, before vitamin E becomes an accepted medical therapy, further long term studies must be undertaken to examine the safety and efficacy of such therapy. An adequate intake of vitamins should be ensured by adherence to a well balanced diet. However, the elderly are prone to circumstances that may prevent them from eating a balanced diet. In addition, there are several age-related medical conditions that may predispose individuals to dietary and vitamin deficiencies. To prevent vitamin deficiency diseases and their associated morbidity, modest vitamin supplementation may be necessary. However, supplementation should be reserved for individuals with documented deficiency or who are at risk of developing such deficiencies, especially those who are homebound or institutionalised. Vitamins taken in large dosages should be considered as drugs. These medicines, which are obtainable over-the-counter, should be carefully regulated to prevent toxicity.
doi_str_mv 10.2165/00002512-199711060-00003
format Article
fullrecord <record><control><sourceid>pubmed_cross</sourceid><recordid>TN_cdi_crossref_primary_10_2165_00002512_199711060_00003</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>9413701</sourcerecordid><originalsourceid>FETCH-LOGICAL-c339t-f257a6f7c0b9dbc7539b26ffb06b6ce6cf7d19b9bb6bf8fb4aa04f550b3ebd103</originalsourceid><addsrcrecordid>eNo9UMtOwzAQtBColMInIOXANWXXru36iCooSJW4AOIWeR1bBCVpZKeH_D3pg-5lR_NYaYexDGHOUclHGIdL5DkaoxFBQb6nxAWbImoz0spcHjDknJvva3aT0u_oUJzjhE3MAoUGnLL5V9XbpmqztOu62je-7W1fbdus__HRdkNWHWDm69LHerhlV8HWyd-d9ox9vjx_rF7zzfv6bfW0yZ0Qps8Dl9qqoB2QKclpKQxxFQKBIuW8ckGXaMgQKQrLQAtrYRGkBBKeSgQxY8vjXRe3KUUfii5WjY1DgVDsGyj-GyjODRwoMUbvj9FuR40vz8HTy6P-cNJtcrYO0bauSmcbByPFaPsDoGhj9A</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Vitamin supplementation therapy in the elderly</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>THURMAN, J. E ; MOORADIAN, A. D</creator><creatorcontrib>THURMAN, J. E ; MOORADIAN, A. D</creatorcontrib><description>Vitamin supplementation in large dosages is increasingly common in the older population. Often, such supplementation is used in an attempt to improve an individual's health status. There have been claims that the effects of vitamins halt the normal aging process or prevent and cure disease. However, several recent studies have failed to demonstrate the efficacy of vitamin supplementation in preventing several types of cancer. In moderate dosages, supplementation with vitamin E (tocopherols) shows promise as a lipid antioxidant, and may reduce the risk of coronary heart disease. However, before vitamin E becomes an accepted medical therapy, further long term studies must be undertaken to examine the safety and efficacy of such therapy. An adequate intake of vitamins should be ensured by adherence to a well balanced diet. However, the elderly are prone to circumstances that may prevent them from eating a balanced diet. In addition, there are several age-related medical conditions that may predispose individuals to dietary and vitamin deficiencies. To prevent vitamin deficiency diseases and their associated morbidity, modest vitamin supplementation may be necessary. However, supplementation should be reserved for individuals with documented deficiency or who are at risk of developing such deficiencies, especially those who are homebound or institutionalised. Vitamins taken in large dosages should be considered as drugs. These medicines, which are obtainable over-the-counter, should be carefully regulated to prevent toxicity.</description><identifier>ISSN: 1170-229X</identifier><identifier>EISSN: 1179-1969</identifier><identifier>DOI: 10.2165/00002512-199711060-00003</identifier><identifier>PMID: 9413701</identifier><language>eng</language><publisher>Auckland: Adis International</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Aging - drug effects ; Antioxidants - therapeutic use ; Ascorbic Acid - therapeutic use ; Avitaminosis - drug therapy ; Biological and medical sciences ; Carotenoids - therapeutic use ; Dietary Supplements ; Drug Interactions ; General and cellular metabolism. Vitamins ; Humans ; Medical sciences ; Middle Aged ; Pharmacology. Drug treatments ; Retinoids - therapeutic use ; Vitamin B Complex - therapeutic use ; Vitamin D - therapeutic use ; Vitamin E - therapeutic use ; Vitamin K - therapeutic use ; Vitamins - adverse effects ; Vitamins - therapeutic use</subject><ispartof>Drugs &amp; aging, 1997-12, Vol.11 (6), p.433-449</ispartof><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-f257a6f7c0b9dbc7539b26ffb06b6ce6cf7d19b9bb6bf8fb4aa04f550b3ebd103</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=2095301$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9413701$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>THURMAN, J. E</creatorcontrib><creatorcontrib>MOORADIAN, A. D</creatorcontrib><title>Vitamin supplementation therapy in the elderly</title><title>Drugs &amp; aging</title><addtitle>Drugs Aging</addtitle><description>Vitamin supplementation in large dosages is increasingly common in the older population. Often, such supplementation is used in an attempt to improve an individual's health status. There have been claims that the effects of vitamins halt the normal aging process or prevent and cure disease. However, several recent studies have failed to demonstrate the efficacy of vitamin supplementation in preventing several types of cancer. In moderate dosages, supplementation with vitamin E (tocopherols) shows promise as a lipid antioxidant, and may reduce the risk of coronary heart disease. However, before vitamin E becomes an accepted medical therapy, further long term studies must be undertaken to examine the safety and efficacy of such therapy. An adequate intake of vitamins should be ensured by adherence to a well balanced diet. However, the elderly are prone to circumstances that may prevent them from eating a balanced diet. In addition, there are several age-related medical conditions that may predispose individuals to dietary and vitamin deficiencies. To prevent vitamin deficiency diseases and their associated morbidity, modest vitamin supplementation may be necessary. However, supplementation should be reserved for individuals with documented deficiency or who are at risk of developing such deficiencies, especially those who are homebound or institutionalised. Vitamins taken in large dosages should be considered as drugs. These medicines, which are obtainable over-the-counter, should be carefully regulated to prevent toxicity.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aging - drug effects</subject><subject>Antioxidants - therapeutic use</subject><subject>Ascorbic Acid - therapeutic use</subject><subject>Avitaminosis - drug therapy</subject><subject>Biological and medical sciences</subject><subject>Carotenoids - therapeutic use</subject><subject>Dietary Supplements</subject><subject>Drug Interactions</subject><subject>General and cellular metabolism. Vitamins</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pharmacology. Drug treatments</subject><subject>Retinoids - therapeutic use</subject><subject>Vitamin B Complex - therapeutic use</subject><subject>Vitamin D - therapeutic use</subject><subject>Vitamin E - therapeutic use</subject><subject>Vitamin K - therapeutic use</subject><subject>Vitamins - adverse effects</subject><subject>Vitamins - therapeutic use</subject><issn>1170-229X</issn><issn>1179-1969</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9UMtOwzAQtBColMInIOXANWXXru36iCooSJW4AOIWeR1bBCVpZKeH_D3pg-5lR_NYaYexDGHOUclHGIdL5DkaoxFBQb6nxAWbImoz0spcHjDknJvva3aT0u_oUJzjhE3MAoUGnLL5V9XbpmqztOu62je-7W1fbdus__HRdkNWHWDm69LHerhlV8HWyd-d9ox9vjx_rF7zzfv6bfW0yZ0Qps8Dl9qqoB2QKclpKQxxFQKBIuW8ckGXaMgQKQrLQAtrYRGkBBKeSgQxY8vjXRe3KUUfii5WjY1DgVDsGyj-GyjODRwoMUbvj9FuR40vz8HTy6P-cNJtcrYO0bauSmcbByPFaPsDoGhj9A</recordid><startdate>19971201</startdate><enddate>19971201</enddate><creator>THURMAN, J. E</creator><creator>MOORADIAN, A. D</creator><general>Adis International</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19971201</creationdate><title>Vitamin supplementation therapy in the elderly</title><author>THURMAN, J. E ; MOORADIAN, A. D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c339t-f257a6f7c0b9dbc7539b26ffb06b6ce6cf7d19b9bb6bf8fb4aa04f550b3ebd103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aging - drug effects</topic><topic>Antioxidants - therapeutic use</topic><topic>Ascorbic Acid - therapeutic use</topic><topic>Avitaminosis - drug therapy</topic><topic>Biological and medical sciences</topic><topic>Carotenoids - therapeutic use</topic><topic>Dietary Supplements</topic><topic>Drug Interactions</topic><topic>General and cellular metabolism. Vitamins</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pharmacology. Drug treatments</topic><topic>Retinoids - therapeutic use</topic><topic>Vitamin B Complex - therapeutic use</topic><topic>Vitamin D - therapeutic use</topic><topic>Vitamin E - therapeutic use</topic><topic>Vitamin K - therapeutic use</topic><topic>Vitamins - adverse effects</topic><topic>Vitamins - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>THURMAN, J. E</creatorcontrib><creatorcontrib>MOORADIAN, A. D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Drugs &amp; aging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>THURMAN, J. E</au><au>MOORADIAN, A. D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vitamin supplementation therapy in the elderly</atitle><jtitle>Drugs &amp; aging</jtitle><addtitle>Drugs Aging</addtitle><date>1997-12-01</date><risdate>1997</risdate><volume>11</volume><issue>6</issue><spage>433</spage><epage>449</epage><pages>433-449</pages><issn>1170-229X</issn><eissn>1179-1969</eissn><abstract>Vitamin supplementation in large dosages is increasingly common in the older population. Often, such supplementation is used in an attempt to improve an individual's health status. There have been claims that the effects of vitamins halt the normal aging process or prevent and cure disease. However, several recent studies have failed to demonstrate the efficacy of vitamin supplementation in preventing several types of cancer. In moderate dosages, supplementation with vitamin E (tocopherols) shows promise as a lipid antioxidant, and may reduce the risk of coronary heart disease. However, before vitamin E becomes an accepted medical therapy, further long term studies must be undertaken to examine the safety and efficacy of such therapy. An adequate intake of vitamins should be ensured by adherence to a well balanced diet. However, the elderly are prone to circumstances that may prevent them from eating a balanced diet. In addition, there are several age-related medical conditions that may predispose individuals to dietary and vitamin deficiencies. To prevent vitamin deficiency diseases and their associated morbidity, modest vitamin supplementation may be necessary. However, supplementation should be reserved for individuals with documented deficiency or who are at risk of developing such deficiencies, especially those who are homebound or institutionalised. Vitamins taken in large dosages should be considered as drugs. These medicines, which are obtainable over-the-counter, should be carefully regulated to prevent toxicity.</abstract><cop>Auckland</cop><pub>Adis International</pub><pmid>9413701</pmid><doi>10.2165/00002512-199711060-00003</doi><tpages>17</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1170-229X
ispartof Drugs & aging, 1997-12, Vol.11 (6), p.433-449
issn 1170-229X
1179-1969
language eng
recordid cdi_crossref_primary_10_2165_00002512_199711060_00003
source MEDLINE; SpringerNature Journals
subjects Adult
Aged
Aged, 80 and over
Aging - drug effects
Antioxidants - therapeutic use
Ascorbic Acid - therapeutic use
Avitaminosis - drug therapy
Biological and medical sciences
Carotenoids - therapeutic use
Dietary Supplements
Drug Interactions
General and cellular metabolism. Vitamins
Humans
Medical sciences
Middle Aged
Pharmacology. Drug treatments
Retinoids - therapeutic use
Vitamin B Complex - therapeutic use
Vitamin D - therapeutic use
Vitamin E - therapeutic use
Vitamin K - therapeutic use
Vitamins - adverse effects
Vitamins - therapeutic use
title Vitamin supplementation therapy in the elderly
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-16T03%3A21%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Vitamin%20supplementation%20therapy%20in%20the%20elderly&rft.jtitle=Drugs%20&%20aging&rft.au=THURMAN,%20J.%20E&rft.date=1997-12-01&rft.volume=11&rft.issue=6&rft.spage=433&rft.epage=449&rft.pages=433-449&rft.issn=1170-229X&rft.eissn=1179-1969&rft_id=info:doi/10.2165/00002512-199711060-00003&rft_dat=%3Cpubmed_cross%3E9413701%3C/pubmed_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/9413701&rfr_iscdi=true