Vitamin supplementation therapy in the elderly
Vitamin supplementation in large dosages is increasingly common in the older population. Often, such supplementation is used in an attempt to improve an individual's health status. There have been claims that the effects of vitamins halt the normal aging process or prevent and cure disease. How...
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Veröffentlicht in: | Drugs & aging 1997-12, Vol.11 (6), p.433-449 |
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description | Vitamin supplementation in large dosages is increasingly common in the older population. Often, such supplementation is used in an attempt to improve an individual's health status. There have been claims that the effects of vitamins halt the normal aging process or prevent and cure disease. However, several recent studies have failed to demonstrate the efficacy of vitamin supplementation in preventing several types of cancer. In moderate dosages, supplementation with vitamin E (tocopherols) shows promise as a lipid antioxidant, and may reduce the risk of coronary heart disease. However, before vitamin E becomes an accepted medical therapy, further long term studies must be undertaken to examine the safety and efficacy of such therapy. An adequate intake of vitamins should be ensured by adherence to a well balanced diet. However, the elderly are prone to circumstances that may prevent them from eating a balanced diet. In addition, there are several age-related medical conditions that may predispose individuals to dietary and vitamin deficiencies. To prevent vitamin deficiency diseases and their associated morbidity, modest vitamin supplementation may be necessary. However, supplementation should be reserved for individuals with documented deficiency or who are at risk of developing such deficiencies, especially those who are homebound or institutionalised. Vitamins taken in large dosages should be considered as drugs. These medicines, which are obtainable over-the-counter, should be carefully regulated to prevent toxicity. |
doi_str_mv | 10.2165/00002512-199711060-00003 |
format | Article |
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However, the elderly are prone to circumstances that may prevent them from eating a balanced diet. In addition, there are several age-related medical conditions that may predispose individuals to dietary and vitamin deficiencies. To prevent vitamin deficiency diseases and their associated morbidity, modest vitamin supplementation may be necessary. However, supplementation should be reserved for individuals with documented deficiency or who are at risk of developing such deficiencies, especially those who are homebound or institutionalised. Vitamins taken in large dosages should be considered as drugs. These medicines, which are obtainable over-the-counter, should be carefully regulated to prevent toxicity.</description><identifier>ISSN: 1170-229X</identifier><identifier>EISSN: 1179-1969</identifier><identifier>DOI: 10.2165/00002512-199711060-00003</identifier><identifier>PMID: 9413701</identifier><language>eng</language><publisher>Auckland: Adis International</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Aging - drug effects ; Antioxidants - therapeutic use ; Ascorbic Acid - therapeutic use ; Avitaminosis - drug therapy ; Biological and medical sciences ; Carotenoids - therapeutic use ; Dietary Supplements ; Drug Interactions ; General and cellular metabolism. Vitamins ; Humans ; Medical sciences ; Middle Aged ; Pharmacology. Drug treatments ; Retinoids - therapeutic use ; Vitamin B Complex - therapeutic use ; Vitamin D - therapeutic use ; Vitamin E - therapeutic use ; Vitamin K - therapeutic use ; Vitamins - adverse effects ; Vitamins - therapeutic use</subject><ispartof>Drugs & aging, 1997-12, Vol.11 (6), p.433-449</ispartof><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-f257a6f7c0b9dbc7539b26ffb06b6ce6cf7d19b9bb6bf8fb4aa04f550b3ebd103</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2095301$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9413701$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>THURMAN, J. E</creatorcontrib><creatorcontrib>MOORADIAN, A. D</creatorcontrib><title>Vitamin supplementation therapy in the elderly</title><title>Drugs & aging</title><addtitle>Drugs Aging</addtitle><description>Vitamin supplementation in large dosages is increasingly common in the older population. Often, such supplementation is used in an attempt to improve an individual's health status. There have been claims that the effects of vitamins halt the normal aging process or prevent and cure disease. However, several recent studies have failed to demonstrate the efficacy of vitamin supplementation in preventing several types of cancer. In moderate dosages, supplementation with vitamin E (tocopherols) shows promise as a lipid antioxidant, and may reduce the risk of coronary heart disease. However, before vitamin E becomes an accepted medical therapy, further long term studies must be undertaken to examine the safety and efficacy of such therapy. An adequate intake of vitamins should be ensured by adherence to a well balanced diet. However, the elderly are prone to circumstances that may prevent them from eating a balanced diet. In addition, there are several age-related medical conditions that may predispose individuals to dietary and vitamin deficiencies. To prevent vitamin deficiency diseases and their associated morbidity, modest vitamin supplementation may be necessary. However, supplementation should be reserved for individuals with documented deficiency or who are at risk of developing such deficiencies, especially those who are homebound or institutionalised. Vitamins taken in large dosages should be considered as drugs. These medicines, which are obtainable over-the-counter, should be carefully regulated to prevent toxicity.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aging - drug effects</subject><subject>Antioxidants - therapeutic use</subject><subject>Ascorbic Acid - therapeutic use</subject><subject>Avitaminosis - drug therapy</subject><subject>Biological and medical sciences</subject><subject>Carotenoids - therapeutic use</subject><subject>Dietary Supplements</subject><subject>Drug Interactions</subject><subject>General and cellular metabolism. Vitamins</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pharmacology. Drug treatments</subject><subject>Retinoids - therapeutic use</subject><subject>Vitamin B Complex - therapeutic use</subject><subject>Vitamin D - therapeutic use</subject><subject>Vitamin E - therapeutic use</subject><subject>Vitamin K - therapeutic use</subject><subject>Vitamins - adverse effects</subject><subject>Vitamins - therapeutic use</subject><issn>1170-229X</issn><issn>1179-1969</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9UMtOwzAQtBColMInIOXANWXXru36iCooSJW4AOIWeR1bBCVpZKeH_D3pg-5lR_NYaYexDGHOUclHGIdL5DkaoxFBQb6nxAWbImoz0spcHjDknJvva3aT0u_oUJzjhE3MAoUGnLL5V9XbpmqztOu62je-7W1fbdus__HRdkNWHWDm69LHerhlV8HWyd-d9ox9vjx_rF7zzfv6bfW0yZ0Qps8Dl9qqoB2QKclpKQxxFQKBIuW8ckGXaMgQKQrLQAtrYRGkBBKeSgQxY8vjXRe3KUUfii5WjY1DgVDsGyj-GyjODRwoMUbvj9FuR40vz8HTy6P-cNJtcrYO0bauSmcbByPFaPsDoGhj9A</recordid><startdate>19971201</startdate><enddate>19971201</enddate><creator>THURMAN, J. E</creator><creator>MOORADIAN, A. D</creator><general>Adis International</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19971201</creationdate><title>Vitamin supplementation therapy in the elderly</title><author>THURMAN, J. E ; MOORADIAN, A. D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c339t-f257a6f7c0b9dbc7539b26ffb06b6ce6cf7d19b9bb6bf8fb4aa04f550b3ebd103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aging - drug effects</topic><topic>Antioxidants - therapeutic use</topic><topic>Ascorbic Acid - therapeutic use</topic><topic>Avitaminosis - drug therapy</topic><topic>Biological and medical sciences</topic><topic>Carotenoids - therapeutic use</topic><topic>Dietary Supplements</topic><topic>Drug Interactions</topic><topic>General and cellular metabolism. Vitamins</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pharmacology. Drug treatments</topic><topic>Retinoids - therapeutic use</topic><topic>Vitamin B Complex - therapeutic use</topic><topic>Vitamin D - therapeutic use</topic><topic>Vitamin E - therapeutic use</topic><topic>Vitamin K - therapeutic use</topic><topic>Vitamins - adverse effects</topic><topic>Vitamins - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>THURMAN, J. E</creatorcontrib><creatorcontrib>MOORADIAN, A. D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Drugs & aging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>THURMAN, J. E</au><au>MOORADIAN, A. D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vitamin supplementation therapy in the elderly</atitle><jtitle>Drugs & aging</jtitle><addtitle>Drugs Aging</addtitle><date>1997-12-01</date><risdate>1997</risdate><volume>11</volume><issue>6</issue><spage>433</spage><epage>449</epage><pages>433-449</pages><issn>1170-229X</issn><eissn>1179-1969</eissn><abstract>Vitamin supplementation in large dosages is increasingly common in the older population. Often, such supplementation is used in an attempt to improve an individual's health status. There have been claims that the effects of vitamins halt the normal aging process or prevent and cure disease. However, several recent studies have failed to demonstrate the efficacy of vitamin supplementation in preventing several types of cancer. In moderate dosages, supplementation with vitamin E (tocopherols) shows promise as a lipid antioxidant, and may reduce the risk of coronary heart disease. However, before vitamin E becomes an accepted medical therapy, further long term studies must be undertaken to examine the safety and efficacy of such therapy. An adequate intake of vitamins should be ensured by adherence to a well balanced diet. However, the elderly are prone to circumstances that may prevent them from eating a balanced diet. In addition, there are several age-related medical conditions that may predispose individuals to dietary and vitamin deficiencies. To prevent vitamin deficiency diseases and their associated morbidity, modest vitamin supplementation may be necessary. However, supplementation should be reserved for individuals with documented deficiency or who are at risk of developing such deficiencies, especially those who are homebound or institutionalised. Vitamins taken in large dosages should be considered as drugs. These medicines, which are obtainable over-the-counter, should be carefully regulated to prevent toxicity.</abstract><cop>Auckland</cop><pub>Adis International</pub><pmid>9413701</pmid><doi>10.2165/00002512-199711060-00003</doi><tpages>17</tpages></addata></record> |
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source | MEDLINE; SpringerNature Journals |
subjects | Adult Aged Aged, 80 and over Aging - drug effects Antioxidants - therapeutic use Ascorbic Acid - therapeutic use Avitaminosis - drug therapy Biological and medical sciences Carotenoids - therapeutic use Dietary Supplements Drug Interactions General and cellular metabolism. Vitamins Humans Medical sciences Middle Aged Pharmacology. Drug treatments Retinoids - therapeutic use Vitamin B Complex - therapeutic use Vitamin D - therapeutic use Vitamin E - therapeutic use Vitamin K - therapeutic use Vitamins - adverse effects Vitamins - therapeutic use |
title | Vitamin supplementation therapy in the elderly |
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