SYNTHESIS, CHARACTERIZATION, DFT MODELING AND IN VITRO ANTIMYCOBACTERIAL ACTIVITY ASSAYS OF A SILVER(I)-ISONIAZID COMPLEX

In the present work, a silver(I) complex with the antimycobacterial drug isoniazid (inh) is described. Elemental and thermogravimetric analyses confirmed a 1:1 metal:ligand ratio for the silver-isoniazid (Ag-inh) complex with molecular composition AgC6H7N3O·NO3. Infrared (IR) analysis suggests a bid...

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Veröffentlicht in:	Química Nova 2021-01, Vol.44 (3), p.278-283
Hauptverfasser:	Paris Junior, José, Cavicchioli, Maurício, Machado, Rachel, Pavan, Fernando, Nakahata, Douglas Hideki, Corbi, Pedro, Costa, Adão, Pereira, Douglas, Massabni, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	antibacterial assays bioinorganic chemistry CHEMISTRY, MULTIDISCIPLINARY metallodrugs molecular modeling Mycobacterium tuberculosis
Online-Zugang:	Volltext
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