TIMOLOL IN CAPILLARY HEMANGIOMA IN INFANT

Background: The purpose of this study was to evaluate the effect of topical timolol in the management of periocular capillary hemangioma. Objective: Efficacy of Timolol in Capillary Hemangioma Methods: A prospective study was performed in 48 consecutive patients with periocularhemangioma. 24 patients underwent topical timolol and Next 24 patientreceived lubricating eye drops topical as a control group.The size of the lesion was measured serially every week during the first month, every 2 weeks for the second month, and then monthly for another 4 months. Therefractive statusand degree of ptosis if present were measured before and at the end of the study. Results: There was reduction in the size of hemangioma, astigmatic error, and degree of ptosisin both the groups. The difference in outcome between two groups was statistically significant. Rebound growth occurred in 22.22% of the group Using timolol and 37.51% of the control group. No adverse effects were reported during or after topical timolol. Conclusion: Topical timolol may have good efficacy fortreatment of infantile periocular hemangioma.