SERUM MAGNESIUM LEVEL IN TYPE2 DIABETES MELLITUS WITH SPECIAL REFERENCE TO DIABETIC RETINOPATHY

SERUM MAGNESIUM LEVEL IN TYPE2 DIABETES MELLITUS WITH SPECIAL REFERENCE TO DIABETIC RETINOPATHY

Background: Diabetes mellitus (DM) is a worldwide, growing epidemic, with an estimated 415 million adults globally. Patients with diabetes are at increased risk of death and a triad of serious diabetes-specific complications (neuropathy, nephropathy, and retinopathy) and other associated complicatio...

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Veröffentlicht in:International journal of advanced research (Indore) 2022-04, Vol.10 (4), p.623-627
Hauptverfasser: R.H, Ahmed, U.R, Pegu, T., Gogoi, B., Devi
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container_title International journal of advanced research (Indore)
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creator R.H, Ahmed
U.R, Pegu
T., Gogoi
B., Devi
description Background: Diabetes mellitus (DM) is a worldwide, growing epidemic, with an estimated 415 million adults globally. Patients with diabetes are at increased risk of death and a triad of serious diabetes-specific complications (neuropathy, nephropathy, and retinopathy) and other associated complications. Magnesium is an intracellular cation and co-enzyme for various reactions of glycolytic pathway. Hence, we evaluated serum magnesium level in type 2 DM with and without diabetic retinopathy. Materials and methods: The study is carried out on 40 patients of type 2 DM with retinopathy and 40 patients of type 2 DM without retinopathy. All patients are subjected to the detailed history taking, ocular examination, and investigations like serum magnesium, FBS, PPBS, glycated hemoglobin. Results: The study revealed that there is a significant decrease in serum magnesium level in diabetic patients with retinopathy than without retinopathy (t= -6.297, df= 58 p=
doi_str_mv 10.21474/IJAR01/14593
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Patients with diabetes are at increased risk of death and a triad of serious diabetes-specific complications (neuropathy, nephropathy, and retinopathy) and other associated complications. Magnesium is an intracellular cation and co-enzyme for various reactions of glycolytic pathway. Hence, we evaluated serum magnesium level in type 2 DM with and without diabetic retinopathy. Materials and methods: The study is carried out on 40 patients of type 2 DM with retinopathy and 40 patients of type 2 DM without retinopathy. All patients are subjected to the detailed history taking, ocular examination, and investigations like serum magnesium, FBS, PPBS, glycated hemoglobin. Results: The study revealed that there is a significant decrease in serum magnesium level in diabetic patients with retinopathy than without retinopathy (t= -6.297, df= 58 p= &lt;0.001).Similarly Fasting Blood sugar, post prandial blood sugar and duration of diabetes also show significant difference. Conclusion: As magnesium level decreases in patients with type 2 DM, the prevalence of retinopathy increases. Timely monitoring of serum magnesium levels and glycated hemoglobin as well as appropriate interventions would be beneficial in early detection and treatment of diabetic retinopathy.</description><identifier>ISSN: 2320-5407</identifier><identifier>EISSN: 2320-5407</identifier><identifier>DOI: 10.21474/IJAR01/14593</identifier><language>eng</language><ispartof>International journal of advanced research (Indore), 2022-04, Vol.10 (4), p.623-627</ispartof><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids></links><search><creatorcontrib>R.H, Ahmed</creatorcontrib><creatorcontrib>U.R, Pegu</creatorcontrib><creatorcontrib>T., Gogoi</creatorcontrib><creatorcontrib>B., Devi</creatorcontrib><creatorcontrib>Associate Profeesor, Department Of Biochemistry, Jorhat Medical College And Hospital, Jorhat, Assam</creatorcontrib><creatorcontrib>Professor and Hod, Department Of Ophthalmology, Jorhat Medical College And Hospital, Jorhat, Assam</creatorcontrib><creatorcontrib>Associate Profeesor, Department Of Medicine,Jorhat Medical College And Hospital, Jorhat, Assam</creatorcontrib><creatorcontrib>Post Graduate Trainee, Department Of Medicine, Jorhat Medical College And Hospital, Jorhat, Assam</creatorcontrib><title>SERUM MAGNESIUM LEVEL IN TYPE2 DIABETES MELLITUS WITH SPECIAL REFERENCE TO DIABETIC RETINOPATHY</title><title>International journal of advanced research (Indore)</title><description>Background: Diabetes mellitus (DM) is a worldwide, growing epidemic, with an estimated 415 million adults globally. Patients with diabetes are at increased risk of death and a triad of serious diabetes-specific complications (neuropathy, nephropathy, and retinopathy) and other associated complications. Magnesium is an intracellular cation and co-enzyme for various reactions of glycolytic pathway. Hence, we evaluated serum magnesium level in type 2 DM with and without diabetic retinopathy. Materials and methods: The study is carried out on 40 patients of type 2 DM with retinopathy and 40 patients of type 2 DM without retinopathy. All patients are subjected to the detailed history taking, ocular examination, and investigations like serum magnesium, FBS, PPBS, glycated hemoglobin. Results: The study revealed that there is a significant decrease in serum magnesium level in diabetic patients with retinopathy than without retinopathy (t= -6.297, df= 58 p= &lt;0.001).Similarly Fasting Blood sugar, post prandial blood sugar and duration of diabetes also show significant difference. 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Conclusion: As magnesium level decreases in patients with type 2 DM, the prevalence of retinopathy increases. Timely monitoring of serum magnesium levels and glycated hemoglobin as well as appropriate interventions would be beneficial in early detection and treatment of diabetic retinopathy.</abstract><doi>10.21474/IJAR01/14593</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
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