Carrier-Mediated Transport of Tetramethyl and Tetraethylammoniums in Isolated Rat Hepatocytes

The uptake mechanism of tetramethylammonium (TMA) and tetraethylammonium (TEA) ions was investigated using the isolated rat hepatocytes. TMA and TEA were trans ported against concentration gradient into the isolated hepatocytes. The cellular uptake of TMA and TEA was inhibited by their structural an...

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Veröffentlicht in:Drug Metabolism and Pharmacokinetics 1994, Vol.9(5), pp.588-595
Hauptverfasser: TSUBAKI, Hidemi, MORI, Izumi, IKEDA, Toshihiko, KOMAI, Toru
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Sprache:eng ; jpn
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