Studies on the Disposition of TSH-01, a New Transdermal System of Estradiol: Absorption and Plasma Concentration in Rats after a Single Transdermal Application

The absorption and plasma levels of radioactivity were studied in female rats following a single transdermal application of 3H-TSH-01 (3H-labeled estradiol, E2). 1. The plasma levels of radioactivity reached the maximum at 4-8 hr after a single transdermal administration of 3H-E2 and then the radioa...

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Veröffentlicht in:Drug Metabolism and Pharmacokinetics 2001/08/30, Vol.16(4), pp.297-303
Hauptverfasser: TANIGUCHI, Kaoru, MOCHIZUKI, Tsutomu, NAGAO, Takeshi, YAMADA, Ichimaro, ARIMA, Noriyuki, HOSHINA, Kenji
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Sprache:eng
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