Pharmacokinetics of Nicardipine following Intravenous and Oral Administration to the Same Human Subject

The pharmacokinetic study of nicardipine in the same human after intravenous and oral adminstration was examined. The profile of nicardipine after bolus 1.05 mg injection fit well to a bi-exponential curve. Plasma nicardipine concentrations for constant rate infusion at 1.27 mg/hr for 3 hr declined...

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Veröffentlicht in:	Drug Metabolism and Pharmacokinetics 1998/08/28, Vol.13(4), pp.376-381
Hauptverfasser:	HIROTA, Noriko, HIRAYAMA, Hiroki, YONEMARU, Makoto, YOSHIKAWA, Osamu, NARUTO, Hiroshi
Format:	Artikel
Sprache:	eng ; jpn
Schlagworte:	Bioavailability Human Nicardipine γ-phase
Online-Zugang:	Volltext
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