Disposition of KW-4679(4): Metabolism of KW-4679 in Rats and Dogs

The metabolism of KW-4679 was investigated in rats and dogs after oral administration of 14C-KW-4679 or KW-4679. 1) After oral administration to rats, N-mono-demethyl-KW-4679 (Ml), N-di-demethyl-KW-4679 (M2), KW-4679 N-oxide (M3), C8-hydroxyl-KW-4679 (M5), M5 sulfate (M4) and oxidated M5 (M6) were i...

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Veröffentlicht in:	Drug Metabolism and Pharmacokinetics 1995, Vol.10(5), pp.689-706
Hauptverfasser:	OHISHI, Takayoshi, MAGARA, Hiroshi, YASUZAWA, Tohru, KOBAYASHI, Hiroyuki, YAMAGUCHI, Kazuo, KOBAYASHI, Satoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiallergic Dog KW-4679 Metabolism Rat
Online-Zugang:	Volltext
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