Disposition of KW-4679 (2) : Absorption, Distribution, Excretion of 14C-KW-4679 after Multiple Oral Administrations in Rats and Effect of KW-4679 on Drug Metabolizing Enzyme in Rats

The disposition of 14C-KW-4679 after a single and repeated oral administration for 21 days to male rats at a dose of 1 mg/kg and the effect of repeated oral administration of KW-4679 to female rats for 7 days on drug metabolizing enzyme system, were studied. 1) Plasma levels of radioactivity collect...

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Veröffentlicht in:	Drug Metabolism and Pharmacokinetics 1995, Vol.10(5), pp.669-682
Hauptverfasser:	OHISHI, Takayoshi, NISHIIE, Hiroyoshi, FUSE, Eiichi, KOBAYASHI, Hiroyuki, KOBAYASHI, Satoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Antiallergic Distribution Enzyme induction Excretion KW-4679 Rat Repeated dosing
Online-Zugang:	Volltext
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