Utility of urinary N-titin as a muscle atrophy biomarker in dexamethasone-induced muscle atrophy model mice

Titin is a giant protein that is specifically expressed in striated muscle and essential for the maintenance of sarcomere structure and function. Recently, the N-terminal fragment of the Titin (N-titin) has been reported to show high levels in human urine in patients with muscular diseases and is ex...

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Veröffentlicht in:Fundamental Toxicological Sciences 2024, Vol.11(4), pp.159-168
Hauptverfasser: Ryoke, Katsunori, Ishizuka, Kana, Yasui, Yuzo, Kondo, Kazuma, Suzuki-Kemuriyama, Noriko, Maekawa, Tatsuya, Miyajima, Katsuhiro
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Sprache:eng
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