JAK/STAT signaling pathway-mediated microRNA-181b promoted blood-brain barrier impairment by targeting sphingosine-1-phosphate receptor 1 in septic rats

Background: Blood-brain barrier (BBB) impairment plays a significant role in the pathogenesis of sepsis-associated encephalopathy (SAE). However, the molecular mechanisms are poorly understood. In the present study, we aimed to investigate the regulatory relationship between the Janus kinase/signal...

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Veröffentlicht in:Annals of translational medicine 2020-11, Vol.8 (21), p.1458-1458, Article 1458
Hauptverfasser: Chen, Sheng-Long, Cai, Geng-Xin, Ding, Hong-Guang, Liu, Xin-Qiang, Wang, Zhong-Hua, Jing, Yuan-Wen, Han, Yong-Li, Jiang, Wen-Qiang, Wen, Miao-Yun
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