Antimicrobial potential of essential oils mouthrinses with and without alcohol: a randomized clinical trial

Aim: This study aimed to compare the microbiological potential and gustatory perception of essential oils (EO) mouthrinses containing and not containing alcohol. Methods: Twenty healthy adult volunteers rinsed with 10mL of the following test solutions: EO with alcohol, EO without alcohol, or a contr...

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Veröffentlicht in:Brazilian journal of oral sciences 2021-04, Vol.20, p.e213867
Hauptverfasser: Grunevald, Matheus, Cantarelli, Rômulo, Oballe, Harry Juan Rivera, Negrini, Thais de Cássia, Arthur, Rodrigo Alex, Silva, Eduardo Liberato da, Herpich, Tiago Luis, Muniz, Francisco Wilker Mustafa Gomes
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container_title Brazilian journal of oral sciences
container_volume 20
creator Grunevald, Matheus
Cantarelli, Rômulo
Oballe, Harry Juan Rivera
Negrini, Thais de Cássia
Arthur, Rodrigo Alex
Silva, Eduardo Liberato da
Herpich, Tiago Luis
Muniz, Francisco Wilker Mustafa Gomes
description Aim: This study aimed to compare the microbiological potential and gustatory perception of essential oils (EO) mouthrinses containing and not containing alcohol. Methods: Twenty healthy adult volunteers rinsed with 10mL of the following test solutions: EO with alcohol, EO without alcohol, or a control solution (saline solution with mint essence). A washout period of at least seven days was adopted after a single-use protocol of the respective solution. All participants used all three tested substances. Antimicrobial potential was assessed by counting salivary total viable bacteria both before and after each rinse. Gustatory perception was evaluated using the Visual Analogue Scale (VAS). Multiple comparisons were performed with the Wilcoxon test, using Bonferroni correction. Results: Both EO solutions presented a higher antimicrobial potential in comparison to the control solution (p
doi_str_mv 10.20396/bjos.v20i00.8663867
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Methods: Twenty healthy adult volunteers rinsed with 10mL of the following test solutions: EO with alcohol, EO without alcohol, or a control solution (saline solution with mint essence). A washout period of at least seven days was adopted after a single-use protocol of the respective solution. All participants used all three tested substances. Antimicrobial potential was assessed by counting salivary total viable bacteria both before and after each rinse. Gustatory perception was evaluated using the Visual Analogue Scale (VAS). Multiple comparisons were performed with the Wilcoxon test, using Bonferroni correction. Results: Both EO solutions presented a higher antimicrobial potential in comparison to the control solution (p&lt;0.017). However, no significant difference in antimicrobial potential was observed between EO containing or not containing alcohol (p=0.218). VAS of EO with alcohol (median: 2.7) was similar to control solution (median: 1.6) (p=0.287). A better gustatory perception was observed of the EO without alcohol (median 7.6) when compared to the control solution (p&lt;0.0001). When EO groups were compared, EO without alcohol also demonstrated a significantly better gustatory perception (p=0.001). Conclusion: Mouthrinse containing EO without alcohol presented a better taste perception when compared to the EO with alcohol, but no difference was observed in the antimicrobial potential of both EO solutions after a single rinse protocol.</description><identifier>ISSN: 1677-3225</identifier><identifier>EISSN: 1677-3225</identifier><identifier>DOI: 10.20396/bjos.v20i00.8663867</identifier><language>eng</language><ispartof>Brazilian journal of oral sciences, 2021-04, Vol.20, p.e213867</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0001-8107-413X ; 0000-0002-3945-1752</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,865,27929,27930</link.rule.ids></links><search><creatorcontrib>Grunevald, Matheus</creatorcontrib><creatorcontrib>Cantarelli, Rômulo</creatorcontrib><creatorcontrib>Oballe, Harry Juan Rivera</creatorcontrib><creatorcontrib>Negrini, Thais de Cássia</creatorcontrib><creatorcontrib>Arthur, Rodrigo Alex</creatorcontrib><creatorcontrib>Silva, Eduardo Liberato da</creatorcontrib><creatorcontrib>Herpich, Tiago Luis</creatorcontrib><creatorcontrib>Muniz, Francisco Wilker Mustafa Gomes</creatorcontrib><title>Antimicrobial potential of essential oils mouthrinses with and without alcohol: a randomized clinical trial</title><title>Brazilian journal of oral sciences</title><description>Aim: This study aimed to compare the microbiological potential and gustatory perception of essential oils (EO) mouthrinses containing and not containing alcohol. Methods: Twenty healthy adult volunteers rinsed with 10mL of the following test solutions: EO with alcohol, EO without alcohol, or a control solution (saline solution with mint essence). A washout period of at least seven days was adopted after a single-use protocol of the respective solution. All participants used all three tested substances. Antimicrobial potential was assessed by counting salivary total viable bacteria both before and after each rinse. Gustatory perception was evaluated using the Visual Analogue Scale (VAS). Multiple comparisons were performed with the Wilcoxon test, using Bonferroni correction. Results: Both EO solutions presented a higher antimicrobial potential in comparison to the control solution (p&lt;0.017). However, no significant difference in antimicrobial potential was observed between EO containing or not containing alcohol (p=0.218). VAS of EO with alcohol (median: 2.7) was similar to control solution (median: 1.6) (p=0.287). A better gustatory perception was observed of the EO without alcohol (median 7.6) when compared to the control solution (p&lt;0.0001). When EO groups were compared, EO without alcohol also demonstrated a significantly better gustatory perception (p=0.001). 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title Antimicrobial potential of essential oils mouthrinses with and without alcohol: a randomized clinical trial
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