Influence of PD-0332991 treatment on cell cycle regulatory genes in breast cancer stem cells

Aim: Palbociclib (PD-0332991) is an inhibitor for cyclin-dependent kinase 4/6 complex and exhibits more activity in luminal ER+ breast cancer. However, sensitivity of breast cancer stem cells (BCSCs) to PD-0332991 treatment and expression patterns of cell cycle regulatory genes after PD-0332991 trea...

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Veröffentlicht in:	Ege tıp dergisi 2018-03, Vol.57 (1), p.36-45
Hauptverfasser:	ONUR ÇAĞLAR, Hasan, YILMAZ SÜSLÜER, Sunde, GÜNDÜZ, Cumhur, HAYDAROĞLU, Ayfer
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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