Overexpression of human CUTA isoform2 enhances the cytotoxicity of copper to HeLa cells

Copper, an essential transient element, can be toxic to cells when present in excess. Altered copper homeostasis is involved in pathological events of many diseases. Human CUTA isoform2 is a member of cation tolerance protein (CutA1) family. In this study, we examined the effect of CUTA isoform2 ove...

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Veröffentlicht in:	Acta biochimica polonica 2008-01, Vol.55 (2), p.411-415
Hauptverfasser:	Yang, Jingchun, Li, Qiang, Yang, Huirong, Yan, Lichong, Yang, Liu, Yu, Long
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - drug effects Apoptosis - genetics Apoptosis - physiology Base Sequence Cell Proliferation - drug effects Cell Survival - drug effects Copper - toxicity DNA Primers - genetics Gene Expression HeLa Cells Humans Membrane Proteins - genetics Membrane Proteins - metabolism Protein Isoforms - genetics Protein Isoforms - metabolism
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