Reduced production, absorption, and elimination of erythropoietin in uremia compared with healthy volunteers

The purpose of this study was to investigate the metabolism of erythropoietin (EPO) in uremia compared with healthy subjects. Twenty-one patients (nine men and 12 women) with end-stage renal failure and anemia and 12 healthy volunteers (3 women and nine men) were studied. The pharmacokinetic paramet...

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Veröffentlicht in:	Journal of the American Society of Nephrology 1994-08, Vol.5 (2), p.177-185
Hauptverfasser:	Jensen, J D, Madsen, J K, Jensen, L W, Pedersen, E B
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Adult Aged Biological Availability Case-Control Studies Erythropoietin - administration & dosage Erythropoietin - biosynthesis Erythropoietin - blood Erythropoietin - pharmacokinetics Female Humans Injections, Intravenous Injections, Subcutaneous Kidney Failure, Chronic - blood Kidney Failure, Chronic - metabolism Male Middle Aged Peritoneal Dialysis, Continuous Ambulatory Recombinant Proteins - administration & dosage Recombinant Proteins - pharmacokinetics Renal Dialysis Uremia - blood Uremia - metabolism
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