Apoptosis and caspase-3 in experimental anti-glomerular basement membrane nephritis

The caspase family is central to the proteolytic events of apoptosis. In particular, caspase-3 plays a key role in the execution of apoptosis. However, the importance of caspase-3 in renal cell apoptosis during kidney scarring has not been established. Here, nephrotoxic nephritis (NTN) was induced i...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2001-03, Vol.12 (3), p.485-495
Hauptverfasser:	BIN YANG, JOHNSON, Timothy S, THOMAS, Graham L, WATSON, Philip F, WAGNER, Bart, EL NAHAS, A. Meguid
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - administration & dosage Apoptosis Base Sequence Basement Membrane - immunology Biological and medical sciences Caspase 3 Caspases - genetics Caspases - metabolism Cell Division Disease Models, Animal DNA Primers - genetics Glomerulonephritis Glomerulonephritis - etiology Glomerulonephritis - metabolism Glomerulonephritis - pathology Kidney - pathology Kidney - physiopathology Kidney Glomerulus - immunology Male Medical sciences Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Proliferating Cell Nuclear Antigen - metabolism Rabbits Rats Rats, Inbred WKY RNA, Messenger - genetics RNA, Messenger - metabolism
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