Inhibition of neutrophil superoxide production by uremic concentrations of guanidino compounds

In uremia, diminished reactive oxygen intermediate production is an important consequence of impaired neutrophil function. The effects of guanidino compounds, which are known uremic toxins, on neutrophil reactive oxygen intermediate production in vitro were studied. Neutrophils from healthy voluntee...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2000-04, Vol.11 (4), p.684-689
Hauptverfasser:	HIRAYAMA, A, NORONHA-DUTRA, A. A, GORDGE, M. P, NEILD, G. H, HOTHERSALL, J. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Biological and medical sciences Cell Adhesion Dose-Response Relationship, Drug Energy Metabolism Fundamental and applied biological sciences. Psychology Guanidines - pharmacology Guanidines - urine Humans Lactic Acid - metabolism Luminescent Measurements Neutrophils - enzymology Neutrophils - metabolism Neutrophils - physiology Nitrates - metabolism Osmolar Concentration Phosphocreatine - metabolism Superoxides - antagonists & inhibitors Superoxides - metabolism Uremia - urine Vertebrates: urinary system
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