Expression of profilin, an actin-binding protein, in rat experimental glomerulonephritis and its upregulation by basic fibroblast growth factor in cultured rat mesangial cells

Profilin binds to actin monomer to regulate actin polymerization, and to phosphatidylinositol 4,5-bisphosphate to inhibit hydrolysis by phospholipase Cgamma1. This study investigated the expression of profilin in rat anti-Thy-1.1 mesangial proliferative glomerulonephritis (GN) and examined the effec...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of the American Society of Nephrology 2000-03, Vol.11 (3), p.423-433
Hauptverfasser:	TAMURA, M, TANAKA, H, HIRANO, H, YASHIRO, A, OSAJIMA, A, OKAZAKI, M, KUDO, H, DOI, Y, FUJIMOTO, S, HIGASHI, K, NAKASHIMA, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Animals Antibodies, Monoclonal - immunology Biological and medical sciences Cell Division - drug effects Cells, Cultured Contractile Proteins Extracellular Matrix Proteins - metabolism Fibroblast Growth Factor 2 - pharmacology Glomerular Mesangium - metabolism Glomerular Mesangium - pathology Glomerulonephritis Glomerulonephritis - immunology Glomerulonephritis - metabolism In Vitro Techniques Kidney Glomerulus - metabolism Male Medical sciences Microfilament Proteins - antagonists & inhibitors Microfilament Proteins - genetics Microfilament Proteins - metabolism Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Oligonucleotides, Antisense - pharmacology Profilins Rats Rats, Wistar Reference Values RNA, Messenger - antagonists & inhibitors RNA, Messenger - metabolism Thy-1 Antigens - immunology Up-Regulation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!