Cellular and molecular crosstalk between leptin receptor and estrogen receptor-α in breast cancer: molecular basis for a novel therapeutic setting

Obesity is associated with an increased risk of breast cancer. A number of adipocytokines are increased in obesity causing low-level chronic inflammation associated with an increased risk of tumors. The adipocytokine leptin shows profound anti-obesity and pro-inflammatory activities. We have hypothe...

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Veröffentlicht in:	Endocrine-related cancer 2010-06, Vol.17 (2), p.373-382
Hauptverfasser:	Fusco, Roberta, Galgani, Mario, Procaccini, Claudio, Franco, Renato, Pirozzi, Giuseppe, Fucci, Laura, Laccetti, Paolo, Matarese, Giuseppe
Format:	Artikel
Sprache:	eng
Schlagworte:	Regular papers
Online-Zugang:	Volltext
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