Subcutaneous Tocilizumab Is Effective for Treatment of Elderly-Onset Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by systemic articular and bone manifestations and its pathogenesis is driven by a complex network of proinflammatory cytokines, including tumor necrosis factor and interleukin (IL)-6. Treatment of rheumatoid arthritis (RA) has been sta...

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Veröffentlicht in:	The Tohoku Journal of Experimental Medicine 2020, Vol.251(1), pp.9-18
Hauptverfasser:	Kondo, Naoki, Fujisawa, Junichi, Endo, Naoto
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age of Onset Aged Anti-Inflammatory Agents - therapeutic use Antibodies, Monoclonal, Humanized - administration & dosage Antibodies, Monoclonal, Humanized - therapeutic use Antirheumatic Agents - administration & dosage Antirheumatic Agents - therapeutic use Arthritis, Rheumatoid - drug therapy Drug Resistance effectiveness elderly onset rheumatoid arthritis Female Humans Injections, Subcutaneous Interleukin-6 - antagonists & inhibitors Male Methotrexate - therapeutic use Middle Aged Prednisolone - therapeutic use retention rate safety Self Administration subcutaneous tocilizumab Treatment Outcome
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